imidazo[4,5-d]triazin-4-one

Names

[ CAS No. ]:
63907-29-9

[ Name ]:
imidazo[4,5-d]triazin-4-one

[Synonym ]:
Imidazo<4,5-d>-1,2,3-triazin-4-on
Imidazotriazinone
2-AZAHYPOXANTHINE,BP STANDARD

Chemical & Physical Properties

[ Density]:
2.22g/cm3

[ Boiling Point ]:
217.5ºC at 760 mmHg

[ Molecular Formula ]:
C₄HN₅O

[ Molecular Weight ]:
135.08400

[ Flash Point ]:
83.4ºC

[ Exact Mass ]:
135.01800

[ PSA ]:
78.87000

[ Index of Refraction ]:
2.087

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: NJ6150000

CHEMICAL NAME :: 4H-Imidazo(4,5-d)-v-triazine, 4-oxo-

CAS REGISTRY NUMBER :: 63907-29-9

LAST UPDATED :: 198910

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C4-H3-N5-O

MOLECULAR WEIGHT :: 137.12

WISWESSER LINE NOTATION :: T56 BN DN FNNNVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3005 mg/kg/21W-C

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Endocrine - adrenal cortex tumors Skin and Appendages - tumors

MUTATION DATA

TYPE OF TEST :: Mutation test systems - not otherwise specified

TEST SYSTEM :: Rodent - rat Cells - not otherwise specified

DOSE/DURATION :: 1 mmol/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 36,2827,1976

Related Compounds

2,3-dihydroimidazo[4,5-d]triazin-4-one
3-ethyl-2H-imidazo[4,5-d]triazin-4-one
3-butyl-2H-imidazo[4,5-d]triazin-4-one
3-phenyl-2H-imidazo[4,5-d]triazin-4-one
7-methyl-1H-imidazo[4,5-d]triazin-4-one
5-methyl-1H-imidazo[4,5-d]triazin-4-one