sodium,[4-[(4-phenyl-1,3-thiazol-2-yl)sulfamoyl]phenyl]azanide

Names

[ CAS No. ]:
63979-88-4

[ Name ]:
sodium,[4-[(4-phenyl-1,3-thiazol-2-yl)sulfamoyl]phenyl]azanide

[Synonym ]:
Sodium sulfathiazole phenyl
Sodium sulfaphenylthiazole
Sulfaphenylthiazole,sodium deriv
Sulfaphenylthiazole sodium

Chemical & Physical Properties

[ Boiling Point ]:
578.5ºC at 760mmHg

[ Molecular Formula ]:
C15H13N3NaO2S2+

[ Molecular Weight ]:
354.40200

[ Flash Point ]:
303.6ºC

[ Exact Mass ]:
354.03500

[ PSA ]:
144.98000

[ LogP ]:
1.55350

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WP1400000
CHEMICAL NAME :
Sulfanilamide, N(sup 1)-(4-phenyl-2-thiazolyl)-, sodium salt
CAS REGISTRY NUMBER :
63979-88-4
LAST UPDATED :
199012
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C15-H13-N3-O2-S2.Na
MOLECULAR WEIGHT :
354.42
WISWESSER LINE NOTATION :
T5N CSJ BMSWR DZ& DR &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,317,1940
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
490 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 71,138,1941
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
390 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIDXA3 Journal of the Indiana State Medical Association. (Indiana State Medical Assoc., 3935 N. Meridian, Indianapolis, IN 46208) V.1- 1908- Volume(issue)/page/year: 33,503,1940
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 43,328,1940

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Fmoc-4-(2,4-dimethoxyphenyl)-L-phenylalanine
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1-(6-Bromoquinazolin-2-yl)pyrrolidin-3-ol
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine