4-(3-AZASPIRO(5.5)UNDEC-3-YL)-4′-FLUORO-BUTYROPHENONE HYDROCHLORIDE

Suppliers

Names

[ CAS No. ]:
64-60-8

[ Name ]:
4-(3-AZASPIRO(5.5)UNDEC-3-YL)-4′-FLUORO-BUTYROPHENONE HYDROCHLORIDE

Chemical & Physical Properties

[ Boiling Point ]:
449.6ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₉ClFNO

[ Molecular Weight ]:
353.90200

[ Flash Point ]:
225.7ºC

[ Exact Mass ]:
353.19200

[ PSA ]:
20.31000

[ LogP ]:
5.57480

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EU1139350

CHEMICAL NAME :: Butyrophenone, 4-(3-azaspiro(5.5)undec-3-yl)-4'-fluoro-, hydrochloride

CAS REGISTRY NUMBER :: 64-60-8

LAST UPDATED :: 198910

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C20-H28-F-N-O.Cl-H

MOLECULAR WEIGHT :: 353.95

WISWESSER LINE NOTATION :: T6N DXTJ A3VR DF& D-& AL6XTJ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Behavioral - analgesia

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - ataxia Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 45 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Behavioral - analgesia

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,62,1965

Related Compounds

1-isochroman-3-yl-N-methyl-methanamine
(R)-tert-butyl (1-(3-chloroquinoxalin-2-yl)pyrrolidin-3-yl)carbamate
6,7-dihydro-4H-thieno[3,2-c]pyran-4-carboxylic acid
(R)-tert-butyl (1-(benzo[d]thiazol-2-yl)pyrrolidin-3-yl)carbamate
(R)-tert-butyl (1-(3H-imidazo[4,5-b]pyridin-2-yl)pyrrolidin-3-yl)carbamate
(R)-tert-butyl (1-(1,1-dioxidobenzo[d]isothiazol-3-yl)pyrrolidin-3-yl)carbamate
(R)-tert-butyl (1-((5-bromothiophen-2-yl)sulfonyl)pyrrolidin-3-yl)carbamate
6,6-dimethyl-5,7-dihydropyrazolo[5,1-b][1,3]oxazine-2-carbonyl chloride
(R)-tert-butyl (1-(thiophen-2-ylsulfonyl)pyrrolidin-3-yl)carbamate
(R)-tert-butyl (1-(2-oxo-2-(1H-pyrrol-2-yl)ethyl)pyrrolidin-3-yl)carbamate

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.