reichstein's substance s 21-acetate

Suppliers

Names

[ CAS No. ]:
640-87-9

[ Name ]:
reichstein's substance s 21-acetate

[Synonym ]:
CORTEXOLONE ACETATE
Einecs 211-369-4
Reichstein substance S 21-acetate
17-Hydroxy-21-acetoxyprogesterone
cortexolone 21-acetate
11-deoxycortisol 21-acetate
21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione
Reichsteins substance S acetate
17-Hydroxy-21-acetoxy-pregnen-(4)-dion-(3.20)
21-Acetoxy-17a-hydroxyprogesterone
21-Acetoxy-17-hydroxy-pregn-4-en-3,20-dion
11-DEOXY-17-HYDROCORTICOSTERONE
11-deoxycortisone acetate

Chemical & Physical Properties

[ Density]:
1.2g/cm3

[ Boiling Point ]:
537.9ºC at 760 mmHg

[ Melting Point ]:
233-235ºC

[ Molecular Formula ]:
C23H32O5

[ Molecular Weight ]:
388.49700

[ Flash Point ]:
181.8ºC

[ Exact Mass ]:
388.22500

[ PSA ]:
80.67000

[ LogP ]:
3.38160

[ Index of Refraction ]:
1.558

[ Water Solubility ]:
Insuluble (8.5E-3 g/L) (25 ºC)

Synthetic Route

Precursor & DownStream

Precursor

  • Isopropenyl acetate
  • Cortodoxone
  • 17,21-dihydroxypregn-4-ene-3,20-dione 17-acetate
  • 17α-hydroxy-20-methoxypregna-4,20-diene-3-one
  • 21-bromo-17α-hydroxy-4-pregnene-3,20-dione
  • Ethanoic anhydride
  • Potassium acetate
  • 17α-Acetoxy-21-chlor-4-pregnen-3,20-dion
  • Epiandrosterone

DownStream

  • Pregn-4-ene-3,20-dione,17,21-bis(acetyloxy)-
  • 3,17α,21-triacetoixypregna-3,5-dien-20-one
  • Androstenedione
  • 5-ALPHA-DIHYDRO SUBSTANCE 'S'
  • Cortodoxone
  • 9α-hydroxycortexolone

Related Compounds

  • 21-acetoxy-17α-hydroxy-5α-pregnane-3,20-dione
  • Cortodoxone-d5
  • Cortodoxone
  • 3beta,17,21-trihydroxy-5beta-pregnan-20-one
  • Aldosterone 18-OxiMe 21-Acetate
  • 16α,17-Epoxycorticosterone 21-Acetate
  • N-(2,4-dimethylphenyl)-2-{[3-(2,4-dimethylphenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}acetamide
  • 2-{[3-(3,5-difluorophenyl)-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl}-N-(2,3-dimethylphenyl)acetamide
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 4-(5-Chloro-2-methylphenyl)piperazine-1-carboximidamide
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 3-{[4-(3-chlorophenyl)piperazin-1-yl]sulfonyl}-N-[(2-fluorophenyl)methyl]-1-methyl-1H-pyrazole-4-carboxamide
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide