5-Bromo-1,3-benzoxazol-2-amine

Suppliers

Names

[ CAS No. ]:
64037-07-6

[ Name ]:
5-Bromo-1,3-benzoxazol-2-amine

[Synonym ]:
2-Amino-5-brom-benzoxazol
5-bromobenzo[d]oxazol-2-amine
2-Benzoxazolamine, 5-bromo-
5-Brom-2-amino-benzoxazol
2-Benzoxazolamine,5-bromo
5-Bromo-1,3-benzoxazol-2-amine
BENZOXAZOLE,2-AMINO-5-BROMO
2-Amino-5-bromobenzoxazole
5-bromo-benzooxazol-2-ylamine

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
340.4±34.0 °C at 760 mmHg

[ Molecular Formula ]:
C7H5BrN2O

[ Molecular Weight ]:
213.031

[ Flash Point ]:
159.7±25.7 °C

[ Exact Mass ]:
211.958511

[ PSA ]:
52.05000

[ LogP ]:
2.64

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.716

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DM4520000
CHEMICAL NAME :
Benzoxazole, 2-amino-5-bromo-
CAS REGISTRY NUMBER :
64037-07-6
LAST UPDATED :
199712
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C7-H5-Br-N2-O
MOLECULAR WEIGHT :
213.05
WISWESSER LINE NOTATION :
T56 BN DOJ CZ HE

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),338,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
160 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),338,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
819 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),336,1964
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
MDCHAG Medicinal Chemistry: A Series of Monographs. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1963- Volume(issue)/page/year: 4(1),336,1964

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Cyanogen bromide
  • 2-Amino-4-bromophenol

DownStream

  • Sapanisertib (MLN0128)
  • 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2-amine
  • 5,7-dibromo-3H-1,3-benzoxazol-2-one
  • 2-AMINO-5,7-DIBROMOBENZOXAZOLE

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 5-Bromo-6-chloro-2-benzoxazolamine
  • 5-bromo-N-Methylbenzo[d]oxazol-2-amine
  • 7-Bromo-1,3-benzoxazol-2-amine
  • 6-Bromo-1,3-benzoxazol-2-amine
  • Ethyl 2-(5-bromobenzo[d]oxazol-2-yl)acetate
  • 3-acetyl-5-bromo-1,3-benzoxazol-2-one
  • 6'-Apo-beta-carotenal
  • (3R)-3-hydroxy-12'-apo-beta-carotenol
  • N-(2-(2-(3-fluorophenyl)thiazolo[3,2-b][1,2,4]triazol-6-yl)ethyl)-1-methyl-3-phenyl-1H-pyrazole-5-carboxamide
  • (S,E)-N-Hydroxy-3-(4-(1-(2-(2-methylpyrazolo[1,5-a]pyridin-3-yl)ethyl)pyrrolidin-2-yl)phenyl)acrylamide
  • 4-(4-methoxyphenyl)-N-(3-methyl-4-(2-oxopyrrolidin-1-yl)phenyl)tetrahydro-2H-pyran-4-carboxamide
  • N-(3-methoxy-4-(2-oxopyrrolidin-1-yl)phenyl)-2-methylthiazole-4-carboxamide
  • N-(3-methoxy-4-(2-oxopyrrolidin-1-yl)phenyl)-2-phenyl-2H-1,2,3-triazole-4-carboxamide
  • 1,3-Dimethyl-4-nitro-N-(2-(thiophen-2-yl)ethyl)-1h-pyrazol-5-amine
  • N-(4-methoxy-3-(2-oxopyrrolidin-1-yl)phenyl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamide
  • 2-(cyclopentylthio)-N-(4-methoxy-3-(2-oxopyrrolidin-1-yl)phenyl)acetamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.