2-(Hydroxymethyl)-2-(o-tolyloxymethyl)-1,3-propanediol

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Names

[ CAS No. ]:
64049-37-2

[ Name ]:
2-(Hydroxymethyl)-2-(o-tolyloxymethyl)-1,3-propanediol

[Synonym ]:
o-Tolyloxy-pentaerythrit
Pentaerythrit-o-tolylether
2-Hydroxymethyl-2-o-tolyloxymethyl-propan-1,3-diol
2-hydroxymethyl-2-o-tolyloxymethyl-propane-1,3-diol

Chemical & Physical Properties

[ Density]:
1.201g/cm3

[ Boiling Point ]:
436.2ºC at 760mmHg

[ Molecular Formula ]:
C12H18O4

[ Molecular Weight ]:
226.26900

[ Flash Point ]:
217.6ºC

[ Exact Mass ]:
226.12100

[ PSA ]:
69.92000

[ LogP ]:
0.33710

[ Index of Refraction ]:
1.559

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TY7756000
CHEMICAL NAME :
1,3-Propanediol, 2-hydroxymethyl-2-(o-tolyloxymethyl)-
CAS REGISTRY NUMBER :
64049-37-2
BEILSTEIN REFERENCE NO. :
1640709
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C12-H18-O4
MOLECULAR WEIGHT :
226.30
WISWESSER LINE NOTATION :
Q1X1Q1Q1OR B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
234 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay)
REFERENCE :
DIPHAH Dissertationes Pharmaceuticae. (Warsaw, Poland) V.1-17, 1949-65. For publisher information, see PJPPAA. Volume(issue)/page/year: 11,223,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
310 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
COREAF Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. (Paris, France) V.1-261, 1835-1965. For publisher information, see CRASEV. Volume(issue)/page/year: 248,3642,1959

Synthetic Route

Click to get detail synthetic route

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