Phenazinium,3,7-bis(acetylamino)-5-phenyl-, chloride (1:1)

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Names

[ CAS No. ]:
64057-64-3

[ Name ]:
Phenazinium,3,7-bis(acetylamino)-5-phenyl-, chloride (1:1)

[Synonym ]:
3,7-bis(methoxycarbonyl)bicyclo<3.3.0>octane-2,6-dione
3,7-bis-acetylamino-5-phenyl-phenazinium,chloride

Chemical & Physical Properties

[ Molecular Formula ]:
C22H19ClN4O2

[ Molecular Weight ]:
406.86500

[ Exact Mass ]:
406.12000

[ PSA ]:
74.97000

[ LogP ]:
0.73150

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SG1610000
CHEMICAL NAME :
Phenazinium, 3,7-diacetamido-5-phenyl-, chloride
CAS REGISTRY NUMBER :
64057-64-3
LAST UPDATED :
199510
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C22-H19-N4-O2.Cl
MOLECULAR WEIGHT :
406.90
WISWESSER LINE NOTATION :
T C666 BK INJ BR& FMV1 LMV1 &Q &G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>450 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 23,63,1962
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>9 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 23,63,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 23,63,1962

Synthetic Route

Precursor & DownStream

Precursor

  • Ethanoic anhydride

DownStream


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-Chloromethyl-5-fluorophenylacetonitrile
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • N-[(2,3-dihydro-1-benzofuran-3-yl)methyl]-2-(trifluoromethyl)benzamide
  • tert-Butyl-DL-alanine