1-[2-(2-cyanoaziridin-1-yl)propan-2-yl]aziridine-2-carboxamide

Names

[ Name ]:
1-[2-(2-cyanoaziridin-1-yl)propan-2-yl]aziridine-2-carboxamide

[Synonym ]:
2-(2-Cyan-aziridin-1-yl)-2-(2-carbamoyl-aziridin-1-yl)-propan
Azimexon
azimexone
Azimexonum [INN-Latin]
Azimexona [Spanish]
Azimexone [Polish]
Azimexona [INN-Spanish]
2-(2-Cyan-aziridinyl-1)-2-(2-carbamoyl-aziridinyl-1)-propan
1-[1-(2-cyano-aziridin-1-yl)-1-methyl-ethyl]-aziridine-2-carboxylic acid amide
EINECS 264-679-7
2-(2-carbamoyl-aziridino)-2-(2-cyano-aziridino)-cyclohexane

Chemical & Physical Properties

[ Density]:
1.29g/cm3

[ Boiling Point ]:
403.4ºC at 760 mmHg

[ Molecular Formula ]:
C₉H₁₄N₄O

[ Molecular Weight ]:
194.23400

[ Flash Point ]:
197.8ºC

[ Exact Mass ]:
194.11700

[ PSA ]:
72.90000

[ Index of Refraction ]:
1.598

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CM6754000

CHEMICAL NAME :: 2-Aziridinecarboxamide, 1-(1-(2-cyano-1-aziridinyl)-1-methylethyl)-

CAS REGISTRY NUMBER :: 64118-86-1

BEILSTEIN REFERENCE NO. :: 0476876

LAST UPDATED :: 199709

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C9-H14-N4-O

MOLECULAR WEIGHT :: 194.27

WISWESSER LINE NOTATION :: T3NTJ BVZ AX1&1&- AT3NTJ BCN

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4370323

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2550 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4370323

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 5,174,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 560 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AITEAT Archivum Immunologiae et Therapiae Experimentalis. (Ars Polona, POB 1001, 00-068 Warsaw 1, Poland) V.10- 1962- Volume(issue)/page/year: 34,333,1986

Related Compounds

tert-butyl N-{5-[4-(hydroxymethyl)piperidin-1-yl]pyridin-2-yl}carbamate
tert-butyl N-methyl-N-(2-oxo-1-{pyrazolo[1,5-a]pyrimidin-6-yl}ethyl)carbamate
2-(1H-imidazol-4-yl)-5-(trifluoromethyl)pyridine
rac-(1R,2S)-2-(2-bromo-3-fluorophenyl)cyclopropan-1-amine
1-[1-(3,4-Difluoro-2-methoxyphenyl)cyclopropyl]cyclopropan-1-amine
2-Methyl-2-(1-phenylcyclopentyl)propan-1-amine
methyl 5-(2-amino-1-hydroxyethyl)-1-methyl-1H-pyrrole-2-carboxylate
1-(2,4-Dimethoxypyridin-3-yl)-2-(methylamino)ethan-1-ol
methyl 5-(2-amino-1,3-oxazol-5-yl)-1-methyl-1H-pyrazole-3-carboxylate
2-(2-Cyclopropyl-1,3-thiazol-4-yl)-2-methoxypropan-1-amine

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