L-phenylalanine, N-[(phenylmethoxy)carbonyl]-, ethenyl ester
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Names
[ CAS No. ]:
64187-42-4
[ Name ]:
L-phenylalanine, N-[(phenylmethoxy)carbonyl]-, ethenyl ester
[Synonym ]:
N-Benzyloxycarbonyl-L-norvalyl-Phe-amid
N-benzyloxycarbonyl-L-phenylalanine vinyl ester
BENZYL N-[1-[(1-CARBAMOYL-2-PHENYL-ETHYL)CARBAMOYL]BUTYL]CARBAMATE
Chemical & Physical Properties
[ Molecular Formula ]:
C19H19NO4
[ Molecular Weight ]:
325.35800
[ Exact Mass ]:
325.13100
[ PSA ]:
64.63000
[ LogP ]:
3.60170
[ Index of Refraction ]:
1.566
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- SQ7600000
- CHEMICAL NAME :
- L-Phenylalanine, N-((phenylmethoxy)carbonyl)-, ethenyl ester
- CAS REGISTRY NUMBER :
- 64187-42-4
- LAST UPDATED :
- 199406
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C19-H19-N-O4
- MOLECULAR WEIGHT :
- 325.39
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,1578,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2001 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 67,1726,1978
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravaginal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravaginal
- DOSE :
- 280 mg/kg
- SEX/DURATION :
- female 28 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 68,696,1979