CGP 12177 hydrochloride

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Names

[ CAS No. ]:
64208-32-8

[ Name ]:
CGP 12177 hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₂₂ClN₃O₃

[ Molecular Weight ]:
315.80

[ Exact Mass ]:
315.13500

[ PSA ]:
90.14000

[ LogP ]:
2.17690

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

ALpha1-adrenoceptor antagonist properties of CGP 12177A and other beta-adrenoceptor ligands: evidence against beta(3)- or atypical beta-adrenoceptors in rat aorta.

Br. J. Pharmacol. 142 , 781-787, (2004)

1. The alpha(1)-adrenoceptor antagonist properties of the beta-adrenoceptor nonconventional partial agonist, CGP 12177A, was investigated in functional assays in rat aorta and in radioligand binding a...

Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wildtype and beta(3)-adrenoceptor knockout mice.

Br. J. Pharmacol. 130 , 747-758, (2000)

The smooth muscle relaxant responses to the mixed beta(3)-, putative beta(4)-adrenoceptor agonist, (-)-CGP 12177 in rat colon are partially resistant to blockade by the beta(3)-adrenoceptor antagonist...

The effects of beta-adrenoceptor agonists on KCl-induced rhythmic contraction in the ureter of guinea pig.

J. Smooth Muscle Res. 36 , 13-19, (2000)

In the present study, we tried to determine what effects were induced by beta-adrenoceptor agonists on 40 mM KCl-induced rhythmic contraction and to clarify which beta-adrenoceptor subtypes are involv...

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