Dichlorophenylphosphine

Names

[ CAS No. ]:
644-97-3

[ Name ]:
Dichlorophenylphosphine

[Synonym ]:
MFCD00000528
Phenylphosphonousdichlorid
Dichlorophenylphosphine
Phosphonous dichloride, P-phenyl-
Phenylphosphonous dichloride
dichloro(phenyl)phosphane
EINECS 211-425-8

Chemical & Physical Properties

[ Density]:
1.319 g/mL at 25 °C(lit.)

[ Boiling Point ]:
224.0±9.0 °C at 760 mmHg

[ Melting Point ]:
−51 °C(lit.)

[ Molecular Formula ]:
C₆H₅Cl₂P

[ Molecular Weight ]:
178.984

[ Flash Point ]:
89.3±18.7 °C

[ Exact Mass ]:
177.950592

[ PSA ]:
13.59000

[ LogP ]:
4.59

[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C

[ Index of Refraction ]:
n20/D 1.597(lit.)

[ Water Solubility ]:
Reacts

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TB2478000

CHEMICAL NAME :: Phosphonous dichloride, phenyl-

CAS REGISTRY NUMBER :: 644-97-3

BEILSTEIN REFERENCE NO. :: 0508189

LAST UPDATED :: 199710

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C6-H5-Cl2-P

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0555341

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0555341

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0555341

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Skin and Appendages - hair

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: 0TS0555341 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84112 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 269 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H314-H335

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R17;R25;R29;R34

[ Safety Phrases ]:
S26-S28-S36/37/39-S43-S45-S28A

[ RIDADR ]:
UN 2845 4.2/PG 1

[ WGK Germany ]:
3

[ RTECS ]:
TB2478000

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
29310095

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Phenylphosphine
phenylphosphonicdichlorid
Tetrachloro(phenyl)phosphorane
Triphenylphosphine
benzene
ethyl phenylphosphonochloridothioite
Cyclohexanone
phenyltrichlorophosphonium hexachlorophosphorate
Diphenylmercury
Triphenylbismuth

DownStream

9-[ethoxy(phenyl)phosphoryl]-N-pentylfluoren-9-amine
trimethyl(phenyl)phosphanium,iodide
9-[ethoxy(phenyl)phosphoryl]fluoren-9-amine
bis(methoxymethyl)-phenylphosphane
Phosphinous bromide,P,P-diphenyl-
2-phenyl-1,3,2-dioxaphospholane
Phosphinic acid, P,P'-(1,2-ethanediyl)bis[2-phenyl-
4-[[4-(dimethylamino)phenyl]-phenylphosphanyl]-N,N-dimethylaniline
bis(2-methoxyphenyl)phenylphosphine
PHENYLTHIOPHOSPHONIC DICHLORIDE

Customs

[ HS Code ]: 2903999090

[ Summary ]:
2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Articles

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Dalton Trans. 45 , 2124-9, (2016)

A series of 2-phosphino-1,3-diphosphonium trifluoromethanesulfonate salts has been prepared and comprehensively characterized. The compounds represent rare examples of salts containing triphosphorus d...

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