Bis(4-nitrophenyl) phosphate

Suppliers

Names

[ CAS No. ]:
645-15-8

[ Name ]:
Bis(4-nitrophenyl) phosphate

[Synonym ]:
Bis(4-nitrophenyl)phosphate
p-nitro-phenohydrogenphosphate
bnpp
Phosphoric acid, bis(4-nitrophenyl) ester
MFCD00007318
Phosphoric acid, bis(p-nitrophenyl) ester
Di-p-nitrophenyl phosphate
Bis(4-nitrophenyl) hydrogen phosphate
Di-4-nitrophenyl phosphate
Bis(p-nitrophenyl)phosphate
DI-P-NITROPHENYLPHOSPHORIC ACID
EINECS 211-434-7

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
545.7±60.0 °C at 760 mmHg

[ Melting Point ]:
172-175 °C(lit.)

[ Molecular Formula ]:
C12H9N2O8P

[ Molecular Weight ]:
340.182

[ Flash Point ]:
283.8±32.9 °C

[ Exact Mass ]:
340.009644

[ PSA ]:
157.21000

[ LogP ]:
1.70

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.642

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB8260000
CHEMICAL NAME :
Phosphoric acid, bis(p-nitrophenyl) ester
CAS REGISTRY NUMBER :
645-15-8
BEILSTEIN REFERENCE NO. :
2064857
LAST UPDATED :
199710
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C12-H9-N2-O8-P

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
410 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
HSZPAZ Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie. (Walter de Gruyter, Inc., 200 Saw Mill River Rd., Hawthorne, NY 10532) V.21- 1895/96- Volume(issue)/page/year: 348,609,1967 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9818 No. of Facilities: 72 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1005 (estimated) No. of Female Employees: 698 (estimated)

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges

[ Hazard Codes ]:
T:Toxic;

[ Risk Phrases ]:
R25

[ Safety Phrases ]:
S45

[ RIDADR ]:
UN 2811 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
TB8260000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • TRIS(4-NITROPHENYL) PHOSPHATE
  • 4-Nitrophenol
  • Diphenyl phosphate
  • DIPHENYL PHOSPHORAMIDATE
  • nitric acid

DownStream

  • 4-Nitrophenol
  • Phosphoric acid,mono(4-nitrophenyl) ester
  • Phenol, 4-nitro-, ion(1-) (9CI)
  • Sodium 4-nitrophenoxide
  • 1-[chloro-(4-nitrophenoxy)phosphoryl]oxy-4-nitrobenzene
  • Methyl 4-nitrophenyl phosphate
  • butyl methyl (4-nitrophenyl) phosphate
  • Tetrakis(4-(hydroxy(oxido)amino)phenyl) diphosphate

Articles

Characterization of Species Differences in Tissue Diltiazem Deacetylation Identifies Ces2a as a Rat-Specific Diltiazem Deacetylase.

Drug Metab. Dispos. 43 , 1218-25, (2015)

Diltiazem, a calcium channel blocker, is mainly metabolized via demethylation or deacetylation in humans. Diltiazem demethylation is catalyzed by cytochrome P450 2D6 and 3A4. Although it was previousl...

Screening of stabilizers for LC-MS/MS analysis of clevidipine and its primary metabolite in dog whole blood.

Bioanalysis 7 , 1457-69, (2015)

Clevidipine is an ester-containing antihypertensive agent that undergoes rapid hydrolysis in blood. A reliable stabilizer cocktail containing citric acid and ascorbic acid was established and the LC-M...

Carboxylesterase 1 as a determinant of clopidogrel metabolism and activation.

J. Pharmacol. Exp. Ther. 344(3) , 665-72, (2013)

Clopidogrel pharmacotherapy is associated with substantial interindividual variability in clinical response, which can translate into an increased risk of adverse outcomes. Clopidogrel, a recognized s...


More Articles

Related Compounds

  • bis(4-nitrophenyl) phosphate
  • ethyl bis(4-nitrophenyl) phosphate
  • Sodium Bis(4-nitrophenyl) Phosphate
  • methyl bis(4-nitrophenyl) phosphate
  • bis(4-nitrophenyl) phosphate hydrate
  • bis(4-nitrophenoxy)phosphoryl bis(4-nitrophenyl) phosphate
  • [(3,4-Difluorophenyl)methyl][(3-fluoro-4-methylphenyl)methyl]amine
  • 2-(4-Chlorobenzamido)-3-(2-oxo-1,2-dihydroquinolin-4-yl)propanoic acid hydrate
  • 1,2-Dimethyl-1H-benzo[d]imidazole-5-sulfonamide
  • 3-Bromo-5-(5-thiazolyl)pyridine
  • (1-Methyl-3-(thiophen-2-yl)-1h-1,2,4-triazol-5-yl)methanamine
  • 4-(3-Fluoropyridin-2-yl)oxybenzoic acid
  • 3-Fluoro-2-(piperidin-4-yloxy)pyridine
  • 2-(Pyrrolidin-2-yl)acetamide hydrochloride
  • N-methyl-1-oxolan-2-ylmethanesulfonamide
  • 1,3-Propanediamine, N3-[(1-cyclohexyl-1H-pyrazol-3-yl)methyl]-N1,N1-dimethyl-
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.