Dopamine

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Names

[ CAS No. ]:
645-31-8

[ Name ]:
Dopamine

[Synonym ]:
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrobromide (1:1)
dopamine hydrobromide
3-hydroxytyramine hydrobromide
4-(2-aminoethyl)benzene-1,2-diol hydrobromide
4-(2-Aminoethyl)pyrocatechol hydrobromide
4-(2-Amino-aethyl)-brenzcatechin,Hydrobromid
MFCD00012897
3,4-Dihydroxyphenethylamine hydrobromide
EINECS 200-110-0
Dopamin-hydrobromid
4-(2-Aminoethyl)-1,2-benzenediol hydrobromide (1:1)
USAF EL-47
EINECS 211-436-8
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrobromide (9CI)
Phenethylamine,3,4-dihydroxy-,hydrobromide
Pyrocatechol, 4-(2-aminoethyl)-, hydrobromide (8CI)
4-(2-Aminoethyl)benzene-1,2-diol hydrobromide (1:1)
Dopamine

Chemical & Physical Properties

[ Boiling Point ]:
337.7ºC at 760 mmHg

[ Melting Point ]:
218-220 °C(lit.)

[ Molecular Formula ]:
C8H12BrNO2

[ Molecular Weight ]:
234.090

[ Flash Point ]:
158ºC

[ Exact Mass ]:
233.005127

[ PSA ]:
66.48000

[ LogP ]:
2.25740

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SH2290150
CHEMICAL NAME :
Phenethylamine, 3,4-dihydroxy-, hydrobromide
CAS REGISTRY NUMBER :
645-31-8
LAST UPDATED :
199206
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H11-N-O2.Br-H
MOLECULAR WEIGHT :
234.12
WISWESSER LINE NOTATION :
Z2R CQ DQ &EH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :
Mutation in mammalian somatic cells
TEST SYSTEM :
Rodent - mouse Lymphocyte
DOSE/DURATION :
20 mg/L
REFERENCE :
EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 11,523,1988

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
S26-S37/39-S37

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
SH2290150

[ HS Code ]:
2922299090

Precursor & DownStream

Precursor

DownStream

  • 1,2,3,4-TETRAHYDRO-6,7-ISOQUINOLINEDIOL HYDROBROMIDE
  • N-acetyldopamine
  • tert-butyl N-[2-(3,4-dihydroxyphenyl)ethyl]carbamate

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Determination of catecholamines in biological tissues by liquid chromatography with coulometric detection.

J. Chromatogr. A. 415(2) , 388-92, (1987)

Impaired dopamine release and uptake in R6/1 Huntington's disease model mice.

Neurosci. Lett. 492(1) , 11-4, (2011)

Huntington's disease (HD) is a progressive, neurodegenerative movement disorder. Here, we used fast-scan cyclic voltammetry to measure dopamine release and uptake in striatal brain slices from R6/1 HD...


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