LAURIC ANHYDRIDE

Names

[ CAS No. ]:
645-66-9

[ Name ]:
LAURIC ANHYDRIDE

[Synonym ]:
MFCD00008965
EINECS 211-449-9
dodecanoyl dodecanoate

Chemical & Physical Properties

[ Density]:
0.899g/cm3

[ Boiling Point ]:
405.4ºC at 760 mmHg

[ Melting Point ]:
41-43ºC(lit.)

[ Molecular Formula ]:
C₂₄H₄₆O₃

[ Molecular Weight ]:
382.62000

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
382.34500

[ PSA ]:
43.37000

[ LogP ]:
7.89800

[ Index of Refraction ]:
1.453

[ Storage condition ]:
−20°C

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2915900090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Lauric acid
Dodecanoyl chloride
Oxalyl chloride
Sodium laurate
Benzoyl chloride
1-decene
Ethanoic anhydride
benzene
Water
1-lauroyl-pyridinium; chloride

DownStream

perfluorolauric acid
propylene glycol dilaurate
propylene glycol laurate
Lauryl aldehyde
DI(N-DODECYL) ETHER
1-Undecene
Lauric acid
laurophenone
1-Dodecanol
Dodecanamide,N-(4-hydroxyphenyl)-

Customs

[ HS Code ]: 2915900090

[ Summary ]:
2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

Articles

Assessment of acylation routes and structural characterisation by liquid chromatography/tandem mass spectrometry of semi-synthetic acyl ester analogues of lipophilic marine toxins.

Rapid Commun. Mass Spectrom. 28(23) , 2605-16, (2014)

Esterification is one of the most important metabolic routes of lipophilic marine toxins in shellfish. In this work we assessed several chemical acylation reactions aimed at obtaining acyl ester analo...

Lauroyl-gemcitabine-loaded lipid nanocapsule hydrogel for the treatment of glioblastoma.

J. Control. Release 225 , 283-93, (2016)

The local delivery of chemotherapeutic agents is a very promising strategy for the treatment of glioblastoma (GBM). Gemcitabine is a chemotherapeutic agent that has a different mechanism of action com...

Immunization with a lipid-conjugated membrane antigen to suppress growth of a fibrosarcoma induced by simian virus 40.

J. Natl. Cancer Inst. 54(5) , 1157-63, (1975)

The covalent conjugation of fatty acid to a tumor cell membrane preparation transformed it from an antigen that enhanced tumor growth to one that suppressed it. A crude cell membrane preparation was m...