1-Piperazineethanol, a-[(4-aminophenoxy)methyl]-4-phenyl-

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Names

[ CAS No. ]:
64511-27-9

[ Name ]:
1-Piperazineethanol, a-[(4-aminophenoxy)methyl]-4-phenyl-

Chemical & Physical Properties

[ Density]:
1.188g/cm3

[ Boiling Point ]:
554.4ºC at 760 mmHg

[ Molecular Formula ]:
C19H25N3O2

[ Molecular Weight ]:
327.42100

[ Flash Point ]:
289.1ºC

[ Exact Mass ]:
327.19500

[ PSA ]:
61.96000

[ LogP ]:
2.41480

[ Index of Refraction ]:
1.613

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TL6844630
CHEMICAL NAME :
1-Piperazineethanol, alpha-((4-aminophenoxy)methyl)-4-phenyl-
CAS REGISTRY NUMBER :
64511-27-9
BEILSTEIN REFERENCE NO. :
0565708
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C19-H25-N3-O2
MOLECULAR WEIGHT :
327.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg
TOXIC EFFECTS :
Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) Behavioral - alteration of classical conditioning
REFERENCE :
IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 15,466,1977

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(4-nitrophenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol
  • 1-(4-Phenylazophenoxy)-3-(N-phenylpiperazino)-2-propanol
  • 4-Nitrophenol

DownStream

  • N-[4-[2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]phenyl]methanesulfonamide

Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • N-(2,4-difluorophenyl)-2-((3-(3-fluorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)thio)acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 4-oxo-6-(((5-propionamido-1,3,4-thiadiazol-2-yl)thio)methyl)-4H-pyran-3-yl 2-methylbenzoate
  • tert-Butyl-DL-alanine