DL-p-Hydroxyphenyllactic acid

Names

[ CAS No. ]:
6482-98-0

[ Name ]:
DL-p-Hydroxyphenyllactic acid

[Synonym ]:
MFCD00010514

Chemical & Physical Properties

[ Density]:
1.404 g/cm3

[ Boiling Point ]:
414.4ºC at 760 mmHg

[ Molecular Formula ]:
C9H10O4

[ Molecular Weight ]:
182.17300

[ Flash Point ]:
218.6ºC

[ Exact Mass ]:
182.05800

[ PSA ]:
77.76000

[ LogP ]:
0.68430

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Precursor & DownStream

Precursor

  • 4-Hydroxyphenylpyruvic acid
  • 4-hydroxybenzaldehyde
  • 2-ACETYL-3-(4-HYDROXYLPHENYL)-ACRYLICACID
  • Methyl p-hydroxyphenyllactate
  • methyl 2-oxo-3-(4-hydroxyphenyl)propionate
  • 4-Amino-L-phenylalanine
  • (+/-)-2-hydroxy-3-(4-hydroxy-3,5-diiodo-phenyl)-propionic acid
  • D-Thr-OH

DownStream

  • 2-(4-HYDROXYPHENYL)ACETALDEHYDE
  • 2-hydroxy-3-(4-hydroxy-3-nitrophenyl)propanoic acid

Articles

Characteristic urine organic acid profile in peroxisomal biogenesis disorders.

J. Inherit. Metab. Dis. 23(4) , 425-8, (2000)

Production of aromatic alpha-hydroxyacids by epimastigotes of Trypanosoma cruzi, and its possible role in NADH reoxidation.

FEMS Microbiol. Lett. 118(1-2) , 89-92, (1994)

Epimastigotes of Trypanosoma cruzi in culture produce and excrete into the medium small amounts of phenyllactic acid and p-hydroxyphenyllactic acids, presumably arising from the catabolism of the arom...

Production of 4-hydroxyphenyllactic acid by Lactobacillus sp. SK007 fermentation.

J. Biosci. Bioeng. 109(4) , 369-71, (2010)

The production of 4-hydroxyphenyllactic acid (4-HO-PLA), a novel antifungal compound, was studied in Lactobacillus sp. SK007 growth. When grown in MRS broth, the strain could produce 75 microg/ml HO-4...


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