Latamoxef

Suppliers

Names

[ CAS No. ]:
64952-97-2

[ Name ]:
Latamoxef

[Synonym ]:
5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid,7-((carboxy(4-hydroxyphenyl)acetyl) amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo
7-((Carboxy(4-hydroxyphenyl)acetyl)amino)-7-methoxy-(3-((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Latamoxef
lamoxactam
(R)-Moxalactam
5-oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylicacid,7-((carboxy(4-hydroxyphen
Listeria MOX Supplement,Moxalactam
Oxa-cephem
yl)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo
LMOX

Chemical & Physical Properties

[ Density]:
1.77 g/cm3

[ Boiling Point ]:
836ºC

[ Melting Point ]:
117 - 122ºC

[ Molecular Formula ]:
C20H20N6O9S

[ Molecular Weight ]:
520.47300

[ Exact Mass ]:
520.10100

[ PSA ]:
231.60000

[ Index of Refraction ]:
1.768

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RN6824500
CHEMICAL NAME :
5-Oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((carboxy(4-hydroxyphenyl)acetyl) amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio) methyl)-8-oxo-
CAS REGISTRY NUMBER :
64952-97-2
LAST UPDATED :
199504
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C20-H20-N6-O9-S
MOLECULAR WEIGHT :
520.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Human - woman
DOSE/DURATION :
480 mg/kg/4D-I
TOXIC EFFECTS :
Blood - hemorrhage
REFERENCE :
AIMEAS Annals of Internal Medicine. (American College of Physicians, 4200 Pine St., Philadelphia, PA 19104) V.1- 1927- Volume(issue)/page/year: 99,126,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5300 No. of Facilities: 69 (estimated) No. of Industries: 1 No. of Occupations: 5 No. of Employees: 5145 (estimated) No. of Female Employees: 4707 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
RN6824500

Articles

A potential substrate binding conformation of β-lactams and insight into the broad spectrum of NDM-1 activity.

Antimicrob. Agents Chemother. 56(10) , 5157-63, (2012)

New Delhi metallo-β-lactamase 1 (NDM-1) is a key enzyme that the pathogen Klebsiella pneumonia uses to hydrolyze almost all β-lactam antibiotics. It is currently unclear why NDM-1 has a broad spectrum...

Comparison of cefoxitin and moxalactam 30 microg disc diffusion methods for detection of methicillin resistance in coagulase-negative staphylococci.

J. Antimicrob. Chemother. 59(4) , 763-6, (2007)

To compare cefoxitin and/or moxalactam 30 microg disc diffusion (DD) methods to detect methicillin resistance in coagulase-negative staphylococci (CoNS) using both high- and low-density (HD/LD) inocul...

Phosphate deprivation is associated with high resistance to latamoxef of gel-entrapped, sessile-like Escherichia coli cells.

J. Antimicrob. Chemother. 49(2) , 315-20, (2002)

Viable Escherichia coli cells were entrapped in agar gel layers and incubated in a phosphate-limited glucose medium. Immobilized bacteria displayed enhanced alkaline phosphatase activity and overexpre...


More Articles

Related Compounds

  • Latamoxef
  • Latamoxef
  • latamoxef
  • latamoxefsodium
  • 2-[(2-Chlorophenoxy)methyl]-I+/-,6-dimethyl-3H-imidazo[4,5-b]pyridine-3-acetic acid
  • 1,1-Dimethylethyl N-[1-[(6-fluoro-2-naphthalenyl)methyl]-4-piperidinyl]carbamate
  • Benzonitrile, 5-(phenylmethoxy)-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
  • 4-Pyridineacetic acid, 3-(chloromethyl)-2-cyano-6-(difluoromethyl)-, ethyl ester
  • rel-(1R,4aR,12aR)-1,2,3,4,4a,5,6,11,12,12a-Decahydro-12a-methyl-1,8-chrysenediol
  • 1-(3-Methyl-1-benzofuran-2-yl)prop-2-en-1-one
  • 2-(2-tert-butyl-2H-1,2,3,4-tetrazol-5-yl)ethanimidamide
  • 2-methyl-1-(1-phenyl-1H-1,2,3-triazol-4-yl)propan-2-amine
  • {1-[4-Fluoro-3-(trifluoromethyl)phenyl]cyclopropyl}methanol
  • 2-Amino-3-[5-(methoxymethyl)furan-2-yl]-3-methylbutanoic acid
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