Acridine Orange hydrochloride

Suppliers

Names

[ CAS No. ]:
65-61-2

[ Name ]:
Acridine Orange hydrochloride

[Synonym ]:
RHODULINE ORANGE
Acridiniumorange-Kation
Acridinorangekation
EUCHRYSINE 3RX
Acridin-orange
acridineorangens
acridineoranger
MFCD00150070
BASIC ORANGE
Zamifenacin fumarate
acridineorangeno
EINECS 200-614-0
Acridine Orange (hydrochloride)

Chemical & Physical Properties

[ Density]:
1.001 g/mL at 20ºC

[ Boiling Point ]:
468.6ºC at 760 mmHg

[ Melting Point ]:
284-287ºC(lit.)

[ Molecular Formula ]:
C₁₇H₂₀ClN₃

[ Molecular Weight ]:
301.81400

[ Flash Point ]:
237.2ºC

[ Exact Mass ]:
301.13500

[ PSA ]:
19.37000

[ LogP ]:
4.32200

[ Index of Refraction ]:
n20/D 1.338

[ Water Solubility ]:
Soluble in water, ethanol, dimethyl sulfoxide

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AR7601000

CHEMICAL NAME :: Acridine, 3,6-bis(dimethylamino)-, monohydrochloride

CAS REGISTRY NUMBER :: 65-61-2

LAST UPDATED :: 199701

DATA ITEMS CITED :: 20

MOLECULAR FORMULA :: C17-H19-N3.Cl-H

MOLECULAR WEIGHT :: 301.85

WISWESSER LINE NOTATION :: T C666 BNJ EN1&1 MN1&1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Micronucleus test

MUTATION DATA

TYPE OF TEST :: DNA adduct

TEST SYSTEM :: Mammal - species unspecified Lymphocyte

DOSE/DURATION :: 10 pph

REFERENCE :: BIPMAA Biopolymers. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10158) V.1- 1963- Volume(issue)/page/year: 11,2537,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3803 No. of Facilities: 29 (estimated) No. of Industries: 1 No. of Occupations: 3 No. of Employees: 625 (estimated) No. of Female Employees: 403 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8883 No. of Facilities: 10 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 114 (estimated) No. of Female Employees: 31 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
AR7601000

[ HS Code ]:
32041300

Articles

3-(3-Hydroxy-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-1,2,5-selenadiazole (G-1103), a novel combretastatin A-4 analog, induces G2/M arrest and apoptosis by disrupting tubulin polymerization in human cervical HeLa cells and fibrosarcoma HT-1080 cells.

Chem. Biol. Interact. 227 , 7-17, (2015)

Microtubule is a popular target for anticancer drugs. In this study, we describe the effect 3-(3-hydroxy-4-methoxyphenyl)-4-(3,4,5-trimethoxyphenyl)-1,2,5-selenadiazole (G-1103), a newly synthesized a...

In vitro inhibition of lysine decarboxylase activity by organophosphate esters.

Biochem. Pharmacol. 92(3) , 506-16, (2014)

Organophosphate esters (OPEs), a major group of organophosphorus flame retardants, are regarded as emerging environmental contaminants of health concern. Amino acid decarboxylases catalyze the convers...

Antiviral effect of methylated flavonol isorhamnetin against influenza.

PLoS ONE 10(3) , e0121610, (2015)

Influenza is an infectious respiratory disease with frequent seasonal epidemics that causes a high rate of mortality and morbidity in humans, poultry, and animals. Influenza is a serious economic conc...