N-acetyl-L-methionine

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Names

[ CAS No. ]:
65-82-7

[ Name ]:
N-acetyl-L-methionine

[Synonym ]:
EINECS 200-617-7
MFCD00064441
N-Acetyl-L-methionine
N-acetyl-methionine
Thiomedon
L-Methionine, N-acetyl-
(2S)-2-acetamido-4-methylsulfanylbutanoic acid
Acetylmethionine
Methionine, N-acetyl-, L-
Methionamine
L-N-Acetyl-Methionine
L-(N-Acetyl)methionine
Ac-Met-OH

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
371.3±52.0 °C at 760 mmHg

[ Melting Point ]:
104-107ºC

[ Molecular Formula ]:
C7H13NO3S

[ Molecular Weight ]:
191.248

[ Flash Point ]:
178.3±30.7 °C

[ Exact Mass ]:
191.061615

[ PSA ]:
91.70000

[ LogP ]:
0.95

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.532

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
PD0480000
CHEMICAL NAME :
Methionine, N-acetyl-
CAS REGISTRY NUMBER :
65-82-7
BEILSTEIN REFERENCE NO. :
1725552
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H13-N-O3-S
MOLECULAR WEIGHT :
191.27
WISWESSER LINE NOTATION :
1VMYVQ2S1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
435 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,262,1970

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
PD0480000

[ HS Code ]:
29309070

Precursor & DownStream

Precursor

  • Acetamide
  • Methional
  • carbon monoxide
  • Methyl acetate
  • DL-Methionine
  • L-Methionine
  • Ethanoic anhydride
  • Methyl mercaptan
  • Acetyl-L-Homoserine lactone
  • N-acetyl-Met-Ala

DownStream

  • N-Acetyl-L-methionine methylester
  • L-Methionine
  • N-Acetyl-DL-methionine

Customs

[ HS Code ]: 29309070

Articles

Importance of product inhibition in the kinetics of the acylase hydrolysis reaction by differential stopped flow microcalorimetry.

Anal. Biochem. 308 , 285-293, (2002)

The hydrolysis of N-acetyl-L-methionine, N-acetylglycine, N-acetyl-L-phenylalanine, and N-acetyl-L-alanine at 298.35K by porcine kidney acylase I (EC 3.5.1.14) was monitored by the heat released upon ...

Model sclerotization studies. 4. Generation of N-acetylmethionyl catechol adducts during tyrosinase-catalyzed oxidation of catechols in the presence of N-acetylmethionine.

Arch. Insect Biochem. Physiol. 38(1) , 44-52, (1998)

Incubation of catechol with mushroom tyrosinase in the presence of N-acetylmethionine resulted in the generation of an adduct. This product was identified to be N-acetylmethionyl catechol, on the basi...

Identification of N-acetylmethionine as the product released during the NH2-terminal processing of a pseudo-class I actin.

J. Biol. Chem. 264(19) , 11491-6, (1989)

Genes for the various isoactins define two classes of actin. Class I actin genes code for Met-Asp(Glu)-actin, and class II actin genes code for Met-X-Asp(Glu)-actin where X is usually cysteine. Amino ...


More Articles


Related Compounds

  • N-Acetyl-L-methionine amide
  • N-acetyl-L-methionine sulfoxide
  • N-acetyl-L-methionine-L-alanine
  • N-acetyl-L-methionine ethyl ester
  • N-Acetyl-L-methionine methylester
  • N-Acetyl-L-methionine sodium salt
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide
  • N-[3-(Aminooxy)propyl]-N-butyl-1-butanamine