2-[2-(methylcarbamoyloxy)ethyl-(phenothiazine-10-carbonyl)amino]ethyl N-methylcarbamate

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Names

[ CAS No. ]:
65240-98-4

[ Name ]:
2-[2-(methylcarbamoyloxy)ethyl-(phenothiazine-10-carbonyl)amino]ethyl N-methylcarbamate

Chemical & Physical Properties

[ Density]:
1.325g/cm3

[ Boiling Point ]:
636.4ºC at 760 mmHg

[ Molecular Formula ]:
C21H24N4O5S

[ Molecular Weight ]:
444.50400

[ Flash Point ]:
338.7ºC

[ Exact Mass ]:
444.14700

[ PSA ]:
125.51000

[ LogP ]:
4.27010

[ Index of Refraction ]:
1.615

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
SN7268000
CHEMICAL NAME :
10H-Phenothiazine-10-carboxamide, N,N-bis(2-(((methylamino)carbonyl)oxy)ethyl)-
CAS REGISTRY NUMBER :
65240-98-4
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C21-H24-N4-O5-S
MOLECULAR WEIGHT :
444.55
WISWESSER LINE NOTATION :
T C666 BN ISJ BVN2OVM1&2OVM1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 12,488,1977

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Phenothiazine
  • N,N-bis(2-hydroxyethyl)phenothiazine-10-carboxamide
  • Methyl isothiocyanate

DownStream

Related Compounds

  • 3-cyclohexyl-3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]propanoic acid
  • 1-(4-methyl-1H-indol-2-yl)methanamine hydrochloride
  • 3-Fluoro-3-(4,5,6,7-tetrahydro-1-benzothiophen-3-yl)propan-1-amine
  • tert-butyl N-[4-(dimethylamino)-2-hydroxy-2-methylbutyl]carbamate
  • 5-Cyanothiophene-2-carbothioamide
  • 4-(6-Chloro-3-iodo-2-pyrazinyl)morpholine
  • 3-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-2-phenylacetamido]-2-hydroxy-2-methylpropanoic acid
  • [(4-Bromothiophen-2-yl)methyl]({[2-(pyrrolidin-1-yl)pyridin-3-yl]methyl})amine
  • 4-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoyl]-2-(methoxymethyl)morpholine-2-carboxylic acid
  • 2,2-Difluoro-3-(quinolin-7-yl)propan-1-amine