Platinate(1-),[1,2,4-benzenetricarboxylato(3-)-kO1,kO2][(1R,2R)-1,2-cyclohexanediamine-kN,kN']-, hydrogen, (SP-4-3)- (9CI)
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Names
[ CAS No. ]:
65296-81-3
[ Name ]:
Platinate(1-),[1,2,4-benzenetricarboxylato(3-)-kO1,kO2][(1R,2R)-1,2-cyclohexanediamine-kN,kN']-, hydrogen, (SP-4-3)- (9CI)
[Synonym ]:
carboxyphthalato-1,2-diaminocyclohexaneplatinum
Chemical & Physical Properties
[ Boiling Point ]:
505.5ºC at 760 mmHg
[ Molecular Formula ]:
C15H16N2O6Pt
[ Molecular Weight ]:
515.37500
[ Exact Mass ]:
515.06600
[ PSA ]:
113.96000
[ LogP ]:
1.68750
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TP1385500
- CHEMICAL NAME :
- Platinate (1-), (1,2,4-benzenetricarboxylato(3-)-O(sup 1),O(sup 2))(1,2-cyclohexanediamine- N,N')-, hydrogen, (SP-4-3)-
- CAS REGISTRY NUMBER :
- 65296-81-3
- LAST UPDATED :
- 199509
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C15-H18-N2-O6-Pt
- MOLECULAR WEIGHT :
- 517.44
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 84 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - effect, not otherwise specified Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 46100 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 40130 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 70 mg/kg/5D-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in bone marrow (not otherwise specified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Bacteria - Escherichia coli
- DOSE/DURATION :
- 33 umol/L
- REFERENCE :
- NEOLA4 Neoplasma. (Karger-Libri, P.O. Box, CH-4009 Basel, Switzerland) V.4- 1957- Volume(issue)/page/year: 34,379,1987