Bestatin hydrochloride

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Names

[ CAS No. ]:
65391-42-6

[ Name ]:
Bestatin hydrochloride

[Synonym ]:
N-[(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-L-leucine hydrochloride (1:1)
MFCD00058004
Bestatin hydrochloride
L-Leucine, N-[(2S,3R)-3-amino-2-hydroxy-1-oxo-4-phenylbutyl]-, hydrochloride (1:1)
Bestatin (hydrochloride)

Chemical & Physical Properties

[ Boiling Point ]:
604.7ºC at 760 mmHg

[ Melting Point ]:
216-218 °C

[ Molecular Formula ]:
C16H25ClN2O4

[ Molecular Weight ]:
344.834

[ Flash Point ]:
319.5ºC

[ Exact Mass ]:
344.150299

[ PSA ]:
112.65000

[ LogP ]:
2.42600

[ Storage condition ]:
−20°C

[ Water Solubility ]:
H2O: 25 mg/mL, clear, colorless

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29242995

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • benzyl N-[(2S,3R)-3-(N-benzyloxycarbonyl)amino-2-hydroxy-4-phenylbutanoyl]-L-leucinate
  • 2-(3-tert-butoxycarbonylamino-2-oxo-4-phenylbutyrylamino)-4-methylpentanoic acid benzyl ester
  • Bestatin methyl ester
  • Phenylnitroethane
  • O-[(2S)-hydroxy-(3R)-3-nitro-4-phenylbutanoyl]-(1'R,2'S,5'R)-8'-phenylmenthol
  • methyl L-leucinate
  • (4R,5S)-4-benzyl-3-[(tert-butoxy)carbonyl]-2,2-dimethyl-1,3-oxazolidine-5-carboxylic acid
  • [(3R)-tert-butoxycarbonylamino-(2S)-hydroxy-2,3-isopropylidene-4-phenylbutanoyl]-L-leucine methyl ester

DownStream

Customs

[ HS Code ]: 29242995

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