N-Benzyl-2-chloronicotinamide

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Names

[ CAS No. ]:
65423-28-1

[ Name ]:
N-Benzyl-2-chloronicotinamide

[Synonym ]:
N-Benzyl-2-chloro-nicotinamide
3-Pyridinecarboxamide, 2-chloro-N-(phenylmethyl)-
2-chloronicotinic acid benzylamine
N-Benzyl-2-chloronicotinamide
MFCD00831758
N-phenylmethyl-2-chloronicotinic acid amide
Nicotinamide,N-benzyl-2-chloro
(2-chloro(3-pyridyl))-N-benzylcarboxamide
2-Chlornicotinsaeure-benzylamid
N3-benzyl-2-chloronicotinamide

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
448.0±40.0 °C at 760 mmHg

[ Melting Point ]:
120ºC

[ Molecular Formula ]:
C13H11ClN2O

[ Molecular Weight ]:
246.692

[ Flash Point ]:
224.8±27.3 °C

[ Exact Mass ]:
246.055984

[ PSA ]:
41.99000

[ LogP ]:
2.34

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.605

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QS4030000
CHEMICAL NAME :
Nicotinamide, N-benzyl-2-chloro-
CAS REGISTRY NUMBER :
65423-28-1
BEILSTEIN REFERENCE NO. :
0402200
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C13-H11-Cl-N2-O
MOLECULAR WEIGHT :
246.71
WISWESSER LINE NOTATION :
T6NJ BG CVM1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
780 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 11(11),78,1977

Safety Information

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Chloronicotinyl chloride
  • Benzylamine
  • 2-Chloronicotinic acid
  • Isobutyl chloroformate
  • 2-Chloro-3-cyanopyridine

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-benzyl-2-(1,2-dihydropyrazol-3-ylidene)indole-5-carboxamide
  • N-benzyl-2-phenylselanylaniline
  • N-benzyl-2-(1,2-dihydropyrazol-3-ylidene)indole-6-carboxamide
  • N-benzyl-2-(2-imino-2-phenylacetyl)benzamide
  • N-benzyl-2-(1,2-dihydropyrazol-3-ylidene)indole-4-carboxamide
  • N-benzyl-2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)acetamide maleate
  • N-(5,7-dimethylbenzo[d]thiazol-2-yl)-2,5-dimethylfuran-3-carboxamide
  • N-(5,7-dimethylbenzo[d]thiazol-2-yl)-2-(N-methylmethylsulfonamido)acetamide
  • N-(6-Chloro-4-methyl-2-benzothiazolyl)-2,3-dihydro-3-methyl-1,4-benzodioxin-2-carboxamide
  • N-Methyl (4-BOC-piperazino)acetamide
  • N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)-2,4-dimethylthiazole-5-carboxamide
  • N-Cyano-N-methylpyrrolidine-1-carboximidamide
  • N-(4-fluoro-1,3-benzothiazol-2-yl)-1H-indole-3-carboxamide
  • 2-((6,7-Difluoro-3,4-dihydroquinolin-1(2H)-yl)methyl)phthalazin-1(2H)-one
  • N-(4,6-difluorobenzo[d]thiazol-2-yl)-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide
  • N-(4,6-difluoro-1,3-benzothiazol-2-yl)-2-(N-methylmethanesulfonamido)acetamide