5-Bromotryptophan

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Names

[ CAS No. ]:
6548-09-0

[ Name ]:
5-Bromotryptophan

[Synonym ]:
T56 BMJ D1YZVQ GE
2-Ammonio-3-(5-bromo-1H-indol-3-yl)propanoate
5-Bromotryptophan
5-bromotryptophan zwitterion
EINECS 229-464-4
2-Amino-3-(5-bromo-1H-indol-3-yl)propanoic acid
Tryptophan, 5-bromo-
2-Amino-3-(5-bromo-1H-indol-3-yl)propionic acid
MFCD00005648

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
495.8±45.0 °C at 760 mmHg

[ Melting Point ]:
264 °C (dec.)(lit.)

[ Molecular Formula ]:
C11H11BrN2O2

[ Molecular Weight ]:
283.121

[ Flash Point ]:
253.7±28.7 °C

[ Exact Mass ]:
282.000397

[ PSA ]:
79.11000

[ LogP ]:
1.89

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.718

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Synthetic Route

Precursor & DownStream

Precursor

  • 5-Bromo-3-methyl-1H-indole
  • 1H-Indole-2-carboxylic acid, 5-bromo-3-methyl-, ethyl ester
  • (4-Bromophenyl)hydrazine hydrochloride
  • 1-(benzenesulfonyl)-5-bromo-3-methylindole
  • 5-Bromoindole
  • diethyl 2-acetamido-2-((5-bromo-1-(phenylsulfonyl)-1H-indol-3-yl)methyl)malonate
  • 1-benzenesulfonyl-5-bromo-3-bromomethylindole
  • 5-Bromogramine

DownStream

  • 4-CYANO-2-PYRIDINECARBOXYLIC ACID
  • 9H-Pyrido[3,4-b]indole, 6-bromo-1-methyl-
  • Boc-Trp(5-Br)-OH

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Analysis of bromotryptophan and hydroxyproline modifications by high-resolution, high-accuracy precursor ion scanning utilizing fragment ions with mass-deficient mass tags.

Anal. Chem. 74(24) , 6230-6, (2002)

Protein modifications are often detected by precursor ion scanning. When quadrupole TOF mass spectrometers are used for precursor ion scanning with high-resolution, high-accuracy fragment ion selectio...

11-fold symmetry of the trp RNA-binding attenuation protein (TRAP) from Bacillus subtilis determined by X-ray analysis.

J. Mol. Biol. 244(1) , 1-5, (1994)

The trp RNA-binding attenuation protein (TRAP) of Bacillus subtilis has been crystallized and examined by crystallography using X-ray synchrotron radiation diffraction data. Crystals of TRAP complexed...

Hemoglobin S antigelation agents based on 5-bromotryptophan with potential for sickle cell anemia.

J. Med. Chem. 33(12) , 3138-42, (1990)

5-Bromotryptophan (5-BrTrp) is the most potent amino acid derivative reported in the literature to inhibit the gelation of hemoglobin S (from sickle cell anemia patients). Trp-Trp is also more potent ...


More Articles


Related Compounds

  • 5-Bromotryptophan
  • 5-bromotryptophan
  • 5-BROMOTRYPTOPHAN ETHYL ESTER
  • DL-5-bromotryptophan methyl ester
  • N-t-butoxycarbonyl-5-bromotryptophan
  • N-(tert-butyloxycarbonyl)-DL-5-bromotryptophan
  • 2-{8-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanoyl]-8-azabicyclo[3.2.1]octan-3-yl}acetic acid
  • 3-{[2-(Pyrrolidin-1-yl)pyridin-3-yl]methyl}azetidin-3-ol
  • 2-{1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentyl]-N-propylformamido}acetic acid
  • 1-[(2-{[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)ethyl]sulfanyl}acetamido)methyl]cyclohexane-1-carboxylic acid
  • 3-[2-cyclopropyl-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]-4-iodobenzoic acid
  • 1-(Ethylamino)-4,5-dimethylheptane-2,4-diol
  • 1,1-Difluoro-2-methyl-5-[(propan-2-yl)amino]pentane-2,4-diol
  • 3,5,5'-trimethyl-5',6'-dihydro-4'H-spiro[cyclohexane-1,7'-thieno[2,3-c]pyridine]
  • 2-[3-(3-Methylbutanamido)pyrrolidin-1-yl]acetic acid
  • 5-cyclopropyl-1-(4-hydroxybutan-2-yl)-1H-1,2,3-triazole-4-carboxamide
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