Methyl 2,6-dichloronicotinate

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Names

[ CAS No. ]:
65515-28-8

[ Name ]:
Methyl 2,6-dichloronicotinate

[Synonym ]:
methyl 2,6-dichloropyridine-3-carboxylate
3-Pyridinecarboxylic acid, 2,6-dichloro-, methyl ester
Methyl 2,6-dichloronicotinate

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
270.5±35.0 °C at 760 mmHg

[ Melting Point ]:
56-60ºC(lit.)

[ Molecular Formula ]:
C7H5Cl2NO2

[ Molecular Weight ]:
206.026

[ Flash Point ]:
117.4±25.9 °C

[ Exact Mass ]:
204.969727

[ PSA ]:
39.19000

[ LogP ]:
1.90

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.548

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22-36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Methanol
  • 2,6-Dichloronicotinic acid
  • Dimethyl sulfate
  • 2,6-Dichloronicotinoyl chloride
  • (Trimethylsilyl)diazomethane

DownStream

  • Methyl 5-bromo-2-methoxy-6-(methylamino)nicotinate
  • methyl 2-chloro-6-phenylpyridine-3-carboxylate
  • Methyl 2-amino-6-chloronicotinate
  • Methyl 6-chloro-2-methoxynicotinate
  • Methyl 2,6-dimethoxynicotinate
  • Methyl 2-chloro-6-methoxynicotinate
  • METHYL 2,6-DIFLUORONICOTINATE
  • methyl 6-chloro-2-ethoxypyridine-3-carboxylate
  • 5-Bromo-2-methoxy-6-(methylamino)nicotinic acid

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Fluoride relay: a new concept for the rapid preparation of anhydrous nucleophilic fluoride salts from KF.

Chem. Commun. (Camb.) , 528, (2007)

Fluoride relay is used to generate exceptionally nucleophilic fluoride reagents from KF on a time scale commensurate with radiotracer synthesis.


More Articles

Related Compounds

  • methyl 2,6-dichloronicotinate N-oxide
  • Methyl 2-amino-4,6-dichloronicotinate
  • methyl 2,6-dihydroxy-4-methoxy-benzoate
  • METHYL 2,6-DIFLUORONICOTINATE
  • Methyl 2,6-dimethylisonicotinate
  • Methyl 2,6-dichloro-5-nitropyrimidine-4-carboxylate
  • 2-(4-Bromophenyl)-2-fluoroethanol
  • [1-(Cyclohexylmethyl)cyclobutyl]methanol
  • {1-[(2,4,6-Trimethylphenyl)methyl]cyclobutyl}methanol
  • 1-((3-Chloropyridin-4-yl)methyl)cyclopropane-1-carboxylic acid
  • {1-[(Thiophen-2-yl)methyl]cyclopropyl}methanol
  • (3-Methylpiperidin-3-yl)methanamine
  • 1-(2-Methylbutyl)cyclopropane-1-carboxylic acid
  • 3-Bromo-1-benzothiophene-5-carbonitrile
  • 1-((2-Methylthiazol-5-yl)methyl)cyclopropane-1-carboxylic acid
  • (1-((1,3-Dimethyl-1h-pyrazol-5-yl)methyl)cyclopropyl)methanamine
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