1-[4-hydroxy-3-trityloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

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Names

[ CAS No. ]:
6554-11-6

[ Name ]:
1-[4-hydroxy-3-trityloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione

[Synonym ]:
2',5'-Di-O-trityl-uridin
2',5'-bis-O-trityluridine
Enzastaurin Hydrochloride
2',5'-Bis-triphenylmethyl-pyrimidin-ribosid
2',5'-di-O-trityluridine
2',5'-ditrityluridine
O2',O5'-ditrityl-uridine

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Molecular Formula ]:
C47H40N2O6

[ Molecular Weight ]:
728.83

[ Exact Mass ]:
728.28900

[ PSA ]:
102.78000

[ LogP ]:
7.18090

[ Index of Refraction ]:
1.705

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Triphenylmethyl Chloride
  • Uridine
  • 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-[[(4-methoxyphenyl)-diphenylmethoxy]methyl]oxolan-2-yl]pyrimidine-2,4-dione
  • 5'-o-trityluridine
  • 4-Methoxytriphenylmethyl chloride

DownStream

  • 1-[4-methylsulfonyloxy-3-trityloxy-5-(trityloxymethyl)oxolan-2-yl]pyrimidine-2,4-dione