Carbamic acid,N-butyl-N-nitroso-, ethyl ester
Suppliers
Names
[ CAS No. ]:
6558-78-7
[ Name ]:
Carbamic acid,N-butyl-N-nitroso-, ethyl ester
[Synonym ]:
N-Nitroso-N-butyl-urethan
N-Butyl-N-nitrosourethan
N-Butyl-N-nitrosourethane
butyl-nitroso-carbamic acid ethyl ester
N-n-Butyl-N-nitroso-urethan
N-Nitrosobutylurethane
1-Butyl-1-nitrosourethan
N-Nitroso-butylurethan
BNUR
TL 478
Butyl-nitroso-carbamidsaeure-aethylester
N-Butyl-N-nitroso ethyl carbamate
N-n-Butyl-N-nitrosourethane
Chemical & Physical Properties
[ Density]:
1.08g/cm3
[ Boiling Point ]:
207.3ºC at 760 mmHg
[ Molecular Formula ]:
C7H14N2O3
[ Molecular Weight ]:
174.19800
[ Flash Point ]:
79.2ºC
[ Exact Mass ]:
174.10000
[ PSA ]:
58.97000
[ LogP ]:
1.92640
[ Index of Refraction ]:
1.468
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EZ1275000
- CHEMICAL NAME :
- Carbamic acid, N-butyl-N-nitroso-, ethyl ester
- CAS REGISTRY NUMBER :
- 6558-78-7
- BEILSTEIN REFERENCE NO. :
- 1780198
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C7-H14-N2-O3
- MOLECULAR WEIGHT :
- 174.23
- WISWESSER LINE NOTATION :
- ONN4&VO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/m3/10M
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg female 20 day(s) after conception
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Endocrine - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2240 mg/kg/8W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 150 mg/kg female 15-21 day(s) after conception
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - transplacental tumorigenesis Reproductive - Tumorigenic effects - testicular tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5300 mg/kg/20W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5040 mg/kg/18W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 5 gm/kg/16W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5 gm/kg/16W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Fibroblast
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 58,1635,1977
Safety Information
[ HS Code ]:
2928000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2928000090
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%