N-dimethoxyphosphoryl-N-ethylethanamine

Names

[ CAS No. ]:
65659-19-0

[ Name ]:
N-dimethoxyphosphoryl-N-ethylethanamine

[Synonym ]:
dimethyl diethylphosphoramidate
Diaethyl-amidophosphorsaeure-dimethylester
diethyl-amidophosphoric acid dimethyl ester
Orthophosphorsaeure-dimethylester-N,N-diethyl-amid
Phosphorsaeure-diaethylamid-dimethylester
O,O-Dimethyl-N,N-diethyl-phosphorsaeureesteramid
O,O-Dimethyl N,N-diethylphosphoramidate
Phosphoramidic acid,diethyl-,dimethyl ester
Diethylphosphoramidic acid dimethyl ester
Phosphorsaeure-dimethylester-<diethylamid>
dimethyl N,N-diethylphosphoramidate

Chemical & Physical Properties

[ Density]:
1.055g/cm3

[ Boiling Point ]:
193.5ºC at 760 mmHg

[ Molecular Formula ]:
C6H16NO3P

[ Molecular Weight ]:
181.17000

[ Flash Point ]:
70.8ºC

[ Exact Mass ]:
181.08700

[ PSA ]:
48.58000

[ LogP ]:
1.72910

[ Index of Refraction ]:
1.425

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB2809000
CHEMICAL NAME :
Phosphoramidic acid, diethyl-, dimethyl ester
CAS REGISTRY NUMBER :
65659-19-0
BEILSTEIN REFERENCE NO. :
1766642
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H16-N-O3-P
MOLECULAR WEIGHT :
181.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ACPMAP Actualites Pharmacologiques. (Paris, France) No.1-33, 1949-81. For publisher information, see JNPHAG. Volume(issue)/page/year: 16,7,1963

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethylamine
  • Dimethyl phosphonate
  • Dimethyl chlorophosphate
  • Diethylphosphoramidic dichloride
  • Sodium Methylate
  • Trimethyl phosphate
  • manganese bis-(diethylamide)
  • Methyl phosphite, (MeO)2(HO)P
  • Dimethylamine
  • N-chloro-N-ethylethanamine

DownStream

Related Compounds

  • DIMETHYL DIMETHYLPHOSPHORAMIDATE
  • N-(benzylsulfonimidoyl)-N-ethylethanamine
  • N-diethylsulfinamoyl-N-ethylethanamine
  • N-(cyclohexylmethyl)-N-ethylethanamine
  • N-benzylsulfanyl-N-ethylethanamine
  • N-diethoxyphosphorylsulfanyl-N-ethylethanamine
  • 6-(1-Methyl-1H-pyrazol-5-yl)picolinaldehyde
  • 6-Bromo-4-(chloromethyl-d2)phthalazin-1(2H)-one
  • N-(3-Acetyl-5-bromo-2-methylphenyl)pivalamide
  • (3-Bromo-6,7-dihydropyrazolo[1,5-A]pyrazin-5(4H)-YL)(cyclopropyl)methanone
  • 6-bromo-7-Benzothiazolecarbonitrile
  • 4-Bromo-2-(carboxycarbonyl)-6-pivalamidobenzoic acid
  • (5-Bromo-3-fluoro-2-methoxypyridin-4-YL)methanol
  • 3-Bromo-6-{[(tert-butoxy)carbonyl]amino}pyridine-2-carboxylic acid
  • 6-Amino-N,N-dimethyl-3-(tetrahydro-2H-pyran-4-yl)-2-pyridinemethanamine
  • 4,4,5,5-Tetramethyl-2-(4'-(trifluoromethyl)-[1,1'-biphenyl]-3-yl)-1,3,2-dioxaborolane