N-dimethoxyphosphoryl-N-ethylethanamine

Names

[ CAS No. ]:
65659-19-0

[ Name ]:
N-dimethoxyphosphoryl-N-ethylethanamine

[Synonym ]:
dimethyl diethylphosphoramidate
Diaethyl-amidophosphorsaeure-dimethylester
diethyl-amidophosphoric acid dimethyl ester
Orthophosphorsaeure-dimethylester-N,N-diethyl-amid
Phosphorsaeure-diaethylamid-dimethylester
O,O-Dimethyl-N,N-diethyl-phosphorsaeureesteramid
O,O-Dimethyl N,N-diethylphosphoramidate
Phosphoramidic acid,diethyl-,dimethyl ester
Diethylphosphoramidic acid dimethyl ester
Phosphorsaeure-dimethylester-<diethylamid>
dimethyl N,N-diethylphosphoramidate

Chemical & Physical Properties

[ Density]:
1.055g/cm3

[ Boiling Point ]:
193.5ºC at 760 mmHg

[ Molecular Formula ]:
C6H16NO3P

[ Molecular Weight ]:
181.17000

[ Flash Point ]:
70.8ºC

[ Exact Mass ]:
181.08700

[ PSA ]:
48.58000

[ LogP ]:
1.72910

[ Index of Refraction ]:
1.425

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TB2809000
CHEMICAL NAME :
Phosphoramidic acid, diethyl-, dimethyl ester
CAS REGISTRY NUMBER :
65659-19-0
BEILSTEIN REFERENCE NO. :
1766642
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H16-N-O3-P
MOLECULAR WEIGHT :
181.20

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
550 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ACPMAP Actualites Pharmacologiques. (Paris, France) No.1-33, 1949-81. For publisher information, see JNPHAG. Volume(issue)/page/year: 16,7,1963

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Diethylamine
  • Dimethyl phosphonate
  • Dimethyl chlorophosphate
  • Diethylphosphoramidic dichloride
  • Sodium Methylate
  • Trimethyl phosphate
  • manganese bis-(diethylamide)
  • Methyl phosphite, (MeO)2(HO)P
  • Dimethylamine
  • N-chloro-N-ethylethanamine

DownStream

Related Compounds

  • DIMETHYL DIMETHYLPHOSPHORAMIDATE
  • N-(benzylsulfonimidoyl)-N-ethylethanamine
  • N-diethylsulfinamoyl-N-ethylethanamine
  • N-(cyclohexylmethyl)-N-ethylethanamine
  • N-benzylsulfanyl-N-ethylethanamine
  • N-diethoxyphosphorylsulfanyl-N-ethylethanamine
  • 2-(3-Azetidinyl)cyclohexanecarboxylic acid
  • (S)-1-(3-methoxyphenyl)-2-methylpropan-1-amine
  • N-benzyl-N-(cyanomethyl)-2,5-dimethylfuran-3-carboxamide
  • N-benzyl-5-bromo-N-(cyanomethyl)furan-2-carboxamide
  • N-benzyl-N-(cyanomethyl)-2-cyclopentylacetamide
  • N-(1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-3-yl)-2-(2,6-diethylphenylamino)acetamide
  • (3R)-7-(Difluoromethyl)-2,3-dihydrobenzo[B]furan-3-ylamine
  • Diethyl 2-nitroisophthalate
  • [3-(1,1-Difluoroethyl)-2-fluoro-phenyl]boronic acid
  • 4-[(1R,2S)-1-amino-2-hydroxypropyl]-3-fluorophenol
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