L-(+)-Lysine monohydrochloride

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Names

[ CAS No. ]:
657-27-2

[ Name ]:
L-(+)-Lysine monohydrochloride

[Synonym ]:
H-Lys-OH.HCl
MFCD00064564
L-Lysinehydrochloride
(2S)-2,6-Diaminohexanoic acid monohydrochloride
L-Lysine, monohydrochloride
L-LYS HCL
Lysine hydrochloride
L-Lysine HCl
LYSINE-L HCL
L-Lysine hydrochloride
LYS,HCL
anhydrous L-lysine monohydrochloride
EINECS 211-519-9
L-Lysine, hydrochloride (1:1)
(S)-2,6-Diaminohexanoic acid monohydrochloride
H-Lys-OH hydrochloride
(S)-2,6-Diaminohexanoic acid hydrochloride
L-Lysine chlorhydrate
L-Lysine, hydrochloride
LYSINE HCL
(2S)-2,6-diaminohexanoic acid hydrochloride
L-Lysine hydrochloride (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
311.5ºC at 760 mmHg

[ Melting Point ]:
263 °C (dec.)(lit.)

[ Molecular Formula ]:
C6H15ClN2O2

[ Molecular Weight ]:
182.648

[ Flash Point ]:
142.2ºC

[ Exact Mass ]:
182.082199

[ PSA ]:
89.34000

[ LogP ]:
1.72990

[ Water Solubility ]:
65 g/100 mL (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OL5650000
CHEMICAL NAME :
Lysine, monohydrochloride, L-
CAS REGISTRY NUMBER :
657-27-2
LAST UPDATED :
199701
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H14-N2-O2.Cl-H
MOLECULAR WEIGHT :
182.68
WISWESSER LINE NOTATION :
Z4YZVQ &GH -L

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 62,49,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
4019 mg/kg
TOXIC EFFECTS :
Behavioral - coma Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
ABBIA4 Archives of Biochemistry and Biophysics. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.31- 1951- Volume(issue)/page/year: 58,253,1955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X3664 No. of Facilities: 612 (estimated) No. of Industries: 4 No. of Occupations: 19 No. of Employees: 5509 (estimated) No. of Female Employees: 1728 (estimated)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S24/25

[ RIDADR ]:
UN 1789 8/PG 3

[ WGK Germany ]:
2

[ RTECS ]:
OL5650000

[ HS Code ]:
29224100

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-[(2R,5S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxy-5-pyrazinyl]butylamine
  • Isobengamide E
  • 4-[(2R,5S)-2,5-Dihydro-2-isopropyl-3,6-dimethoxy-5-pyrazinyl]butyronitrile
  • D-glucopyranose

DownStream

  • L(-)-Pipecolinic acid
  • N2-[(Benzyloxy)Carbonyl]-N6-(Trifluoroacetyl)-L-Lysine
  • Z-Lys(Z)-OH
  • Cadaverine
  • 2-Cyanopiperidine
  • Ethyl 2,6-diaminohexanoate dihydrochloride
  • Pipecolic acid
  • L-Lysine
  • 2-Piperidone

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

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Related Compounds

  • L(+)-Lysine monohydrate
  • H-Lys(Me)2-OH·HCl
  • DL-Lysine monohydrochloride
  • L(+)-Ornithine hydrochloride
  • L-(+)-Arginine Hydrochloride
  • L-Lysine hydrochloride
  • N-(2-((2'-(Di-m-tolylmethyl)-1H,1'H-[3,3'-biindol]-2-yl)methyl)phenyl)acetamide
  • N-(2-((2'-Benzhydryl-1H,1'H-[3,3'-biindol]-2-yl)methyl)phenyl)ethanethioamide
  • N-(2-((2'-Benzhydryl-6-fluoro-1H,1'H-[3,3'-biindol]-2-yl)methyl)-5-fluorophenyl)acetamide
  • N-(2-((2'-Benzhydryl-1H,1'H-[3,3'-biindol]-2-yl)methyl)phenyl)acetamide
  • N-(2-((2'-Benzhydryl-1H,1'H-[3,3'-biindol]-2-yl)methyl)phenyl)butyramide
  • (2S,3R)-2-amino-3-hydroxy-4-(4-nitrophenyl)butanoate
  • (S)-Ethyl 7-bromo-1-(4-methoxybenzamido)-2-oxo-3-((propoxycarbonyl)amino)-2,3-dihydro-1H-benzo[e]indole-1-carboxylate
  • (S)-Ethyl 7-methoxy-1-(4-methoxybenzamido)-2-oxo-3-((propoxycarbonyl)amino)-2,3-dihydro-1H-benzo[e]indole-1-carboxylate
  • (S)-Ethyl 1-(4-methoxybenzamido)-7-methyl-2-oxo-3-((propoxycarbonyl)amino)-2,3-dihydro-1H-benzo[e]indole-1-carboxylate
  • (S)-Ethyl 3-benzamido-1-(4-methoxybenzamido)-2-oxo-2,3-dihydro-1H-benzo[e]indole-1-carboxylate
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