2-Chloro-6-trifluoromethylpyridine

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Names

[ CAS No. ]:
65753-47-1

[ Name ]:
2-Chloro-6-trifluoromethylpyridine

[Synonym ]:
Pyridine, 2-chloro-3-(trifluoromethyl)-
MFCD00042223
T6NJ BG CXFFF
6-chloro-5-trifluoromethylpyridine
2-Chloro-6-(trifluoromethyl)pyridine
2-Chloro-3-trifluoro methylpyridine
6-Chloro-2-trifluoromethylpyridine
Pyridine, 2-chloro-6-(trifluoromethyl)-
EINECS 424-520-6
2-Chloro-3-(trifluoromethyl)pyridine
2-Chloro-6-trifluoromethylpyridine

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
181.7±35.0 °C at 760 mmHg

[ Melting Point ]:
36-40 °C(lit.)

[ Molecular Formula ]:
C6H3ClF3N

[ Molecular Weight ]:
181.543

[ Flash Point ]:
63.7±25.9 °C

[ Exact Mass ]:
180.990616

[ PSA ]:
12.89000

[ LogP ]:
2.51

[ Vapour Pressure ]:
1.1±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.447

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301 + H311-H314-H372-H412

[ Precautionary Statements ]:
P273-P280-P301 + P310 + P330-P303 + P361 + P353-P304 + P340 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P2 (EN 143) respirator cartridges;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
F:Flammable

[ Risk Phrases ]:
R11;R25;R36/37/38

[ Safety Phrases ]:
S16-S22-S36/37/39-S45

[ RIDADR ]:
UN 2926 4.1/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3-trifluoromethylpyridine N-oxide
  • (Trifluoromethyl)trimethylsilane
  • 2-Chloro-3-iodopyridine
  • 3-trifluoromethylpyridine

DownStream

  • 3-(Trifluoromethyl)-2-pyridinecarbonitrile
  • 3-trifluoromethylpyridine
  • Bibenzyl
  • 5-(trifluoromethyl)-2-[5-(trifluoromethyl)pyridin-2-yl]pyridine
  • 2-Benzyl-3-trifluoromethylpyridine
  • 1-[3-(TRIFLUOROMETHYL)PYRID-2-YL]-1,4-DIAZEPANE
  • 3-(Trifluoromethyl)pyridine-2-carboxylic acid
  • 1-[3-(trifluoromethyl)pyrid-2-yl]piperazine
  • (3-Trifluoromethylpyrid-2-yl)hydrazine
  • 5-Iodo-3-(trifluoromethyl)-2-pyridinol

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Trifluoromethyl-Substituted Pyridines Through Displacement of Iodine by in situ Generated (Trifluoromethyl) copper. Cottet F and Schlosser M.

European J. Org. Chem. 2 , 327-330, (2002)

Modified Ullmann coupling of 2-chloro-3-trifluoromethylpyridine. Munavalli S, et al.

J. Fluor. Chem. 73(1) , 1-6, (1995)


More Articles

Related Compounds

  • 2-Chloro-6-trifluoromethylpyridine
  • 4-bromo-2-chloro-6-(trifluoromethyl)pyridine
  • 3-Bromo-2-chloro-6-(trifluoromethyl)pyridine
  • 3-amino-2-chloro-6-(trifluoromethyl)pyridine
  • 2-Chloro-6-(trifluoromethyl)-3-pyridinamine
  • 3,5-Dibromo-2-chloro-6-(trifluoromethyl)pyridine
  • Benzoic acid, 2-(2-oxopropyl)-, ion(1-)
  • N,N-diethyl-4-(nitromethyl)aniline
  • 2-(3-Ethynylphenyl)-2-methyloxirane
  • 3-(1-Bromo-2-methylpropan-2-yl)-2-methoxypyridine
  • 5-(3-Aminopropoxy)thiophene-3-carbonitrile
  • 3-bromo-5-methoxy-4-[(2S)-oxiran-2-yl]pyridine
  • 3-Bromo-2-chloro-5-(1-ethynylcyclopropyl)thiophene
  • Methyl 3-amino-2-(2-fluoropyridin-3-yl)propanoate
  • 2-[(3-Methylazetidin-3-yl)oxy]-5-nitropyridine
  • 1-[2-(4-Fluorophenyl)ethyl]cyclobutane-1-carbonitrile
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