3,4-Difluoro phenyl acetic acid

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Names

[ CAS No. ]:
658-93-5

[ Name ]:
3,4-Difluoro phenyl acetic acid

[Synonym ]:
(3,4-Difluorophenyl)acetic acid
EINECS 211-527-2
Benzeneacetic acid, 3,4-difluoro-
2-(3,4-Difluorophenyl)acetic acid
3,4-Difluorobenzeneacetic acid
QV1R CF DF
MFCD00010002
3,4-Difluoro phenyl acetic acid

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
263.8±25.0 °C at 760 mmHg

[ Melting Point ]:
46-50 °C(lit.)

[ Molecular Formula ]:
C8H6F2O2

[ Molecular Weight ]:
172.129

[ Flash Point ]:
113.3±23.2 °C

[ Exact Mass ]:
172.033585

[ PSA ]:
37.30000

[ LogP ]:
1.52

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.508

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,2-Difluorobenzene
  • 3,4-Difluorobenzyl chloride
  • 2-(3,4-Difluorophenyl)acetonitrile

DownStream

  • 3-(3,4-Difluorophenyl)-4-(4-(methylsulfonyl)phenyl)-2(5H)-furanone
  • 3,4-DIFLUOROPHENYLACETIC ACID METHYL ESTER
  • 3,4-Difluorophenyl acetyl chloride
  • ALPHA-BROMO-4-FLUOROPHENYLACETIC ACID 9

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Synthesis and Biological Evaluation of Fluorinated 3-Phenylcoumarin-7-O-Sulfamate Derivatives as Steroid Sulfatase Inhibitors.

Chem. Biol. Drug Des. 87 , 233-8, (2016)

In the present work, we report the initial results of our study on a series of 3-phenylcoumarin sulfamate-based compounds containing C-F bonds as novel inhibitors of steroid sulfatase. The new compoun...

Chromatographic separation of 3,4-difluorophenylacetic acid and its positional isomers using five different techniques.

J. Chromatogr. A. 866(2) , 281-92, (2000)

The separation of five positional isomers from 3,4-difluorophenylacetic acid was investigated using normal- and reversed-phase high-performance liquid chromatography, capillary zone electrophoresis, g...


More Articles

Related Compounds

  • AMINO-(3,4-DIFLUORO-PHENYL)-ACETIC ACID HCL
  • (3,4-dimethoxy-phenyl)-acetic acid-(2,4-dimethoxy-anilide)
  • (3,4-dimethoxy-phenyl)-acetic acid-(3,4-dimethoxy-phenacylamide)
  • (3,4-dimethoxy-phenyl)-acetic acid-(2-cyclohexa-1,4-dienyl-ethylamide)
  • (3,4-dimethoxy-phenyl)-acetic acid-(β-hydroxy-3,4-dimethoxy-phenethylamide)
  • (3,4-dimethoxy-phenyl)-acetic acid-(3,4,β-trimethoxy-phenethylamide)