2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid

Suppliers

Names

[ Name ]:
2-(2-Aminothiazole-4-yl)-2-methoxyiminoacetic acid

[Synonym ]:
ThiazoxiMic Acid
4-Thiazoleacetic acid, 2-amino-α-(methoxyimino)-, (αZ)-
(2Z)-(2-Amino-1,3-thiazol-4-yl)(methoxyimino)acetic acid
Aminothiaoximoacid
EINECS 265-957-0
ATIFICIALCOW-BEZOAR
MFCD00071528
Aminothiaoximinoacid
syn-Thiazoximic acid
Cefepime Impurity 4

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
425.1±37.0 °C at 760 mmHg

[ Melting Point ]:
192 °C (dec.)(lit.)

[ Molecular Formula ]:
C₆H₇N₃O₃S

[ Molecular Weight ]:
201.203

[ Flash Point ]:
210.9±26.5 °C

[ Exact Mass ]:
201.020813

[ PSA ]:
126.04000

[ LogP ]:
-0.11

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.689

[ Storage condition ]:
-20?C Freezer

[ Water Solubility ]:
0.6 g/100 mL (20 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2934100090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Ethyl 2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate
methyl (Z)-2-amino-alpha-(methoxyimino)thiazol-4-acetate
2-methoxyimino-3-oxo-4,4-dibromobutyric acid
carbathion
(Z)-[2-(Chloroacetamido)thiazole-4-yl]methoxyiminoacetic acid
S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiolacetate

DownStream

2-BENZOTHIAZOLYL-3-(4-CARBOXY-2-METHOXYPHENYL)-5-[4-(2-SULFOETHYLCARBAMOYL)PHENYL]-2H-TETRAZOLIUM
(Z)-[2-(Chloroacetamido)thiazole-4-yl]methoxyiminoacetic acid
1-[2-(Z)-Methoxyimino-2-(2-aminothiazol-4-yl)acetoxy]benzotrizole

Customs

[ HS Code ]: 2934100090

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

Diazald, a newly recognized antimicrobial agent and its spectrophotometric determination.

Acta Microbiol. Hung. 39(3-4) , 317-22, (1992)

Diazald, a chemical intermediate for the synthesis of biologically active compounds, was found to be a potent in vitro antimicrobial agent against yeasts, yeast-like and filamentous fungi as well as G...

Total Synthesis of Sodium (3S, 4R)-3-[2-(2-Aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-4-methoxymethyl-2-azetidinone-1-sulfonate from D-Aspartic Acid. Chung BY, et al.

Bull. Korean Chem. Soc. 13(3) , 315-16, (1992)

Total Synthesis of Sodium (3R, 4S)-3-(2-(2-Aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido)-4-methoxymethyl-2-azetidinone-1-sulfonate from L-Aspartic Acid. Chung BY, et al.

Bull. Korean Chem. Soc. 13(3) , 311-14, (1992)

2-(2-Aminothiazole-4-yl)-2-hydroxyiminoacetic acid
2-(2-Aminothiazole-4-yl)-2-[2-(tert-butoxycarbonyl)-methoxyimino]acetic acid
2-MERCAPTOBENZOTHIAZOLEYL(Z)-2-AMINOTHIAZOL-4-YL-2-METHOXYIMINO ACETATE(MAEM)
(Z)-2-(2-Aminothiazole-4-yl-)-2-trityloxyimino acetic acid
(Z)-2-(2-Tritylaminothiazol-4-yl)-2-methoxyiminoacetic acid
(Z)-2-(2-tert-butoxycarbonylaminothiazol-4-yl)-2-methoxyiminoacetic acid
7-Ethyl-2-(2-methylpropyl)-[1,2,4]triazolo[1,5-a]pyridin-5-ol
tert-butyl N-[3-(2-oxobut-3-en-1-yl)cyclobutyl]carbamate
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
(4-Methyl-tetrahydro-furan-2-yl)-methanol
2-Fluoro-1-(3-fluoropyridin-4-yl)ethan-1-ol
N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde