4-hydroxy-1,1-dioxo-N-pyridin-2-yl-2H-1λ6,2-benzothiazine-3-carboxamide

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Names

[ CAS No. ]:
65897-46-3

[ Name ]:
4-hydroxy-1,1-dioxo-N-pyridin-2-yl-2H-1λ6,2-benzothiazine-3-carboxamide

[Synonym ]:
Desmethyl piroxicam
Piroxicam Impurity B

Chemical & Physical Properties

[ Density]:
1.611g/cm3

[ Molecular Formula ]:
C14H11N3O4S

[ Molecular Weight ]:
317.32000

[ Exact Mass ]:
317.04700

[ PSA ]:
120.26000

[ LogP ]:
3.29790

[ Index of Refraction ]:
1.727

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Saccharin
  • 3-Oxo-1,2-benzoisothiazoline-2[N-(2-pyridyl)]acetamide 1,1-Dioxide
  • methyl 2-(N-(2-oxo-2-(pyridin-2-ylamino)ethyl)sulfamoyl)benzoate
  • 2-Aminopyridine
  • (1,1,2,3,3,3-HEXAFLUOROPROPYL)-1,4-DIOXANE,RACEMIC
  • 2-[1,1-dioxide-3-oxo-1,2-benzisothiazole-2(3H)-yl] acetic acid chloride

DownStream

  • Piroxicam

Related Compounds

  • 2,5-Dimethyl-3-[3-(piperidine-1-carbonyl)piperidin-1-yl]pyrazine
  • 2-(Methylsulfanyl)-4-[3-(pyridin-3-yloxy)piperidin-1-yl]pyrimidine-5-carbonitrile
  • N-tert-butyl-1-(cyclopentylmethyl)piperidine-3-carboxamide
  • 4-{[1-(6-Methylpyrazin-2-yl)piperidin-4-yl]methoxy}pyridine-2-carboxamide
  • 4-{[1-(4-Methylpyrimidin-2-yl)piperidin-4-yl]methoxy}pyridine-2-carboxamide
  • 4-{[1-(1-Methyl-6-oxo-1,6-dihydropyrimidin-4-yl)piperidin-4-yl]methoxy}pyridine-2-carboxamide
  • 4-{[1-(2-Methylpyrimidin-4-yl)piperidin-4-yl]methoxy}pyridine-2-carboxamide
  • 5-Chloro-2-[3-(pyrrolidine-1-carbonyl)azetidin-1-yl]pyridine
  • N-tert-butyl-1-{5,6-dimethylthieno[2,3-d]pyrimidin-4-yl}azetidine-3-carboxamide
  • 5-Bromo-2-[3-(pyridin-3-yloxy)piperidin-1-yl]pyridine-3-carbonitrile
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