AMG-517

Suppliers

Names

[ CAS No. ]:
659730-32-2

[ Name ]:
AMG-517

[Synonym ]:
BD-0082
N-(4-(6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide
UNII-172V4FBZ75
N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)-1,3-benzothiazol-2-yl]acetamide
Acetamide, N-[4-[[6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-
N-[4-({6-[4-(Trifluoromethyl)phenyl]-4-pyrimidinyl}oxy)-1,3-benzothiazol-2-yl]acetamide
N-[4-[[6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-acetamide
AMG-517
N-(4-(6-(4-trifluoromethylphenyl)pyrimidin-4-yloxy)benzothiazol-2-yl)acetamide
N-(4-[6-(4-trifluoromethyl-phenyl)-pyrimidin-4-yloxy]-benzothiazol-2-yl)-acetamide
AMG517
AMG 517

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
227ºC

[ Molecular Formula ]:
C20H13F3N4O2S

[ Molecular Weight ]:
430.403

[ Exact Mass ]:
430.071136

[ PSA ]:
108.73000

[ LogP ]:
5.41

[ Index of Refraction ]:
1.645

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-[6-(4-trifluoromethylphenyl)pyrimidin-4-yloxy]benzothiazol-2-ylamine
  • Ethanoic anhydride
  • 4-Chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine
  • 2-amino-1,3-benzothiazol-4-ol

DownStream

Related Compounds

  • N-[4-[6-[4-[1-(4-fluorophenyl)ethyl]piperazin-1-yl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide
  • AMG 837 hemicalcium salt
  • AMG-416
  • AMG 837 (calcium hydrate)
  • AMG 8718
  • AMG-510(Sotorasib)
  • {4-[(4-Fluorophenyl)sulfonyl]piperazino}(7-methylimidazo[1,2-a]pyridin-2-yl)methanone
  • 1-(4-Methyl-2-phenyl-1,3-thiazole-5-carbonyl)-4-(2-phenylethenesulfonyl)piperazine
  • 1-[4-(2-Phenylethenesulfonyl)piperazin-1-yl]-2-[2-(thiophen-3-yl)-1,3-thiazol-4-yl]ethan-1-one
  • N-{3-[(azepan-2-ylidene)sulfamoyl]phenyl}-3,6-dichloropyridine-2-carboxamide
  • 1-(3,6-Dichloropyridine-2-carbonyl)-4-(4-methylbenzenesulfonyl)piperazine
  • N-(5-(N-(2-Chlorophenyl)sulfamoyl)-2-methoxyphenyl)-2-phenylthiazole-4-carboxamide
  • N-(2-((3-(2-chlorophenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)oxy)ethyl)thiophene-2-sulfonamide
  • 1-(3,6-Dichloropyridine-2-carbonyl)-4-(2,5-dimethylbenzenesulfonyl)piperazine
  • 2,4,6-Trimethyl-7-oxo-1,3,5-cycloheptatrien-1-yl 3-methylbenzoate
  • Methyl 2-(piperidin-3-yl)benzoate
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