AMG-517

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Names

[ CAS No. ]:
659730-32-2

[ Name ]:
AMG-517

[Synonym ]:
BD-0082
N-(4-(6-(4-(trifluoromethyl)phenyl)pyrimidin-4-yloxy)benzo[d]thiazol-2-yl)acetamide
UNII-172V4FBZ75
N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)-1,3-benzothiazol-2-yl]acetamide
Acetamide, N-[4-[[6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-
N-[4-({6-[4-(Trifluoromethyl)phenyl]-4-pyrimidinyl}oxy)-1,3-benzothiazol-2-yl]acetamide
N-[4-[[6-[4-(trifluoromethyl)phenyl]-4-pyrimidinyl]oxy]-2-benzothiazolyl]-acetamide
AMG-517
N-(4-(6-(4-trifluoromethylphenyl)pyrimidin-4-yloxy)benzothiazol-2-yl)acetamide
N-(4-[6-(4-trifluoromethyl-phenyl)-pyrimidin-4-yloxy]-benzothiazol-2-yl)-acetamide
AMG517
AMG 517

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
227ºC

[ Molecular Formula ]:
C20H13F3N4O2S

[ Molecular Weight ]:
430.403

[ Exact Mass ]:
430.071136

[ PSA ]:
108.73000

[ LogP ]:
5.41

[ Index of Refraction ]:
1.645

[ Storage condition ]:
-20℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 4-[6-(4-trifluoromethylphenyl)pyrimidin-4-yloxy]benzothiazol-2-ylamine
  • Ethanoic anhydride
  • 4-Chloro-6-(4-(trifluoromethyl)phenyl)pyrimidine
  • 2-amino-1,3-benzothiazol-4-ol

DownStream

Related Compounds

  • N-[4-[6-[4-[1-(4-fluorophenyl)ethyl]piperazin-1-yl]pyrimidin-4-yl]oxy-1,3-benzothiazol-2-yl]acetamide
  • AMG 837 hemicalcium salt
  • AMG-416
  • AMG 837 (calcium hydrate)
  • AMG 8718
  • AMG-510(Sotorasib)
  • (1,1-Difluorospiro[2.4]heptan-5-yl)methanamine
  • 2-[4-(Trifluoromethoxy)phenyl]tetrazole-5-carboxylic acid
  • 4-Pyridin-3-yl-5-pyridin-4-yl-1,3-thiazol-2-amine
  • 4-Amino-1,1,1-trifluoro-2-(5-methyl-1,3-oxazol-2-yl)butan-2-ol
  • 4-Amino-1,1,1-trifluoro-2-(1,3-oxazol-2-yl)butan-2-ol
  • methyl 5H,6H,7H,8H,9H-imidazo[1,2-a][1,4]diazepine-6-carboxylate
  • 5H,6H,7H,8H,9H-imidazo[1,2-a][1,4]diazepine-6-carboxylic acid
  • 2-[[1-(9H-Fluoren-9-ylmethoxycarbonyl)pyrrolidin-3-yl]methyl]-4-methyl-1,3-thiazole-5-carboxylic acid
  • Tert-butyl 7-imino-7-oxo-7lambda6-thia-1-azaspiro[4.4]nonane-1-carboxylate
  • 3,3-Dimethyl-2-oxo-3a,4,5,6,7,7a-hexahydro-1H-indole-5-carboxylic acid
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