PHENIPRAZINE HYDROCHLORIDE

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Names

[ CAS No. ]:
66-05-7

[ Name ]:
PHENIPRAZINE HYDROCHLORIDE

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₅ClN₂

[ Molecular Weight ]:
186.68200

[ Exact Mass ]:
186.09200

[ PSA ]:
38.05000

[ LogP ]:
2.97410

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MV7400000

CHEMICAL NAME :: Hydrazine, (alpha-methylphenethyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 66-05-7

LAST UPDATED :: 199206

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C9-H14-N2.Cl-H

MOLECULAR WEIGHT :: 186.71

WISWESSER LINE NOTATION :: ZM1Y1&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 18,617,1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 59 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 5,125,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 112 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay)

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,20,1975

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 87 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 5,125,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: IJNEAQ International Journal of Neuropharmacology. (New York, NY) V.1-8, 1962-69. For publisher information, see NEPHBW. Volume(issue)/page/year: 5,125,1966

Related Compounds

Pheniprazine hydrochloride
Tyrocidine, hydrochloride
Triprolidine hydrochloride
Minoxidil hydrochloride
Elacridar hydrochloride
dodecylamine hydrochloride
ethyl 4-hydroxy-5-(4-methanesulfonyl-1H-pyrazol-1-yl)pentanoate
N-[(6-chloropyridin-3-yl)methyl]-4-cyclopropyloxolan-3-amine
rac-1-{[(3aR,6aR)-octahydrocyclopenta[b]pyrrol-3a-yl]methyl}-3-(2-methoxyethyl)urea
1-methyl-2,4-dioxo-1H,2H,3H,4H-pyrido[2,3-d]pyrimidine-6-sulfonyl fluoride
Tert-butyl 4-(aminomethyl)-1-oxa-7-azaspiro[4.4]nonane-7-carboxylate
Ethyl (2E)-4-bromo-2-(ethoxymethylidene)-4,4-difluoro-3-oxobutanoate
2-formyl-5H,6H,8H-imidazo[2,1-c][1,4]oxazine-3-carboxylic acid
5-bromo-3-(1H-pyrazol-4-yl)-2-Pyridinamine
2'-Bromo-2,7-dimethyl-9,9'-spirobi[fluorene]
{6-Chloro-[1,2,4]triazolo[4,3-b]pyridazin-3-yl}methyl cycloheptanecarboxylate

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