D-Glucosamine hydrochloride
Suppliers
Names
[ CAS No. ]:
66-84-2
[ Name ]:
D-Glucosamine hydrochloride
[Synonym ]:
EINECS 200-638-1
MFCD00135831
Glucopyranose, 2-amino-2-deoxy-, hydrochloride, D-
Glucosamine (hydrochloride)
Chemical & Physical Properties
[ Boiling Point ]:
449.9ºC at 760 mmHg
[ Melting Point ]:
190-194ºC
[ Molecular Formula ]:
C6H14ClNO5
[ Molecular Weight ]:
215.632
[ Flash Point ]:
225.9ºC
[ Exact Mass ]:
215.056046
[ PSA ]:
124.01000
[ Index of Refraction ]:
72 ° (C=1， H2O)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LZ6665000
- CHEMICAL NAME :
- D-Glucose, 2-amino-2-deoxy-, hydrochloride
- CAS REGISTRY NUMBER :
- 66-84-2
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C6-H13-N-O5.Cl-H
- MOLECULAR WEIGHT :
- 215.66
- WISWESSER LINE NOTATION :
- VHYZYQYQYQ1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 15 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - sensory change involving peripheral nerve
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 6200 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - sensory change involving peripheral nerve
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 5 gm/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - sensory change involving peripheral nerve
MUTATION DATA
- TEST SYSTEM :
- Fish - not otherwise specified
- DOSE/DURATION :
- 1000 ppm
- REFERENCE :
- NULSAK Nucleus (Calcutta). (Dr. A.K. Sharma, Centre of Advanced Studies in Cell and Chromosome Research, Calcutta, 35 Baliygunge Circular Rd., Calcutta 700 019, India) V.1- 1958- Volume(issue)/page/year: 28,176,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - T2043 No. of Facilities: 1651 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 16143 (estimated) No. of Female Employees: 13164 (estimated)
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
F: Flammable;Xi: Irritant;Xn: Harmful;
[ Risk Phrases ]:
R21
[ Safety Phrases ]:
S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
LZ6665000
[ HS Code ]:
2932999099
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922399090
[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
FEBS J. 281(16) , 3591-608, (2014)
Glucose provides an essential nutrient source that supports glycolysis and the hexosamine biosynthesis pathway (HBP) to maintain tumour cell growth and survival. Here we investigated if short-term glu...
Anal. Bioanal. Chem 406(19) , 4765-75, (2014)
During wheat digestion, gluten-derived proteolytic resistant peptides are generated, some of them involved in celiac disease. In vitro digestion models able to mimic the peptides generated in the huma...
Pharm. Dev. Technol. 20(1) , 74-83, (2015)
The solid dispersion technique is one of the most effective methods for improving the dissolution rate of poorly water-soluble drugs; however this is reliant on a suitable carrier and solvent being se...