2-Chloro-1,3,2-Dioxaphospholane 2-oxide

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Names

[ Name ]:
2-Chloro-1,3,2-Dioxaphospholane 2-oxide

[Synonym ]:
2-Chloro-1,3,2-Dioxaphospholane 2-oxide
2-Chloro-1,3,2-dioxaphospholane-2-oxide
2-Chloro-1,3,2-dioxaphospholane-2-oxyde
1,3,2-Dioxaphospholane, 2-chloro-, 2-oxide
EINECS 229-560-6
2-chloro-1,3,2λ<sup>5</sup>-dioxaphospholane 2-oxide
MFCD00043138

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
96.7±9.0 °C at 760 mmHg

[ Melting Point ]:
12-14 °C

[ Molecular Formula ]:
C₂H₄ClO₃P

[ Molecular Weight ]:
142.478

[ Flash Point ]:
-88.9±26.4 °C

[ Exact Mass ]:
141.958664

[ PSA ]:
45.34000

[ LogP ]:
1.38010

[ Vapour Pressure ]:
49.3±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.435

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C: Corrosive;

[ Risk Phrases ]:
R14;R34

[ Safety Phrases ]:
S26-S36/37/39-S45-S8-S25

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

2-methoxy-1,3,2λ5-dioxaphospholane 2-oxide
2-Hydroxy-1,3,2-dioxaphospholane 2-oxide
C16-PAF
1-O-octadecyl-2-acetyl-sn-glycero-3-phosphocholine
rac-3-Octadecanamido-2-ethoxypropan-1-ol Phosphocholine
2-phenoxy-1,3,2λ5-dioxaphospholane 2-oxide
2-hexadecoxy-1,3,2λ5-dioxaphospholane 2-oxide
2-phenylmethoxy-1,3,2λ5-dioxaphospholane 2-oxide
2-(2-methoxyethoxy)-1,3,2λ5-dioxaphospholane 2-oxide
Triethylammonium chloride

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Preparation and in vitro antimicrobial activity of silver-bearing degradable polymeric nanoparticles of polyphosphoester-block-poly(L-lactide).

ACS Nano 9(2) , 1995-2008, (2015)

The development of well-defined polymeric nanoparticles (NPs) as delivery carriers for antimicrobials targeting human infectious diseases requires rational design of the polymer template, an efficient...

Synthesis of BODIPY-labeled alkylphosphocholines with leishmanicidal activity, as fluorescent analogues of miltefosine.

Bioorg. Med. Chem. Lett. 18 , 6336-9, (2008)

Two general synthetic methods are described, by which the highly fluorescent and photostable BODIPY group can be inserted in and aligned with the alkyl backbone of linear lipids. These methods have be...

J. Am. Chem. Soc. 115 , 6600, (1993)

2-(1'-methyl-2'-chloropropoxy)-2-oxo-4,5-dimethyl-1,3,2-dioxaphospholane
2-Chloro-1,3,2-dioxaphospholane
2-butoxy-1,3,2-dioxaphospholane 2-oxide
2-nonyloxy-[1,3,2]dioxaphospholane 2-oxide
2-Hydroxy-1,3,2-dioxaphospholane 2-oxide
2-isopropyl-1,3,2-dioxaphospholane-2-oxide