6-methoxypyridin-3-amin

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Names

[ CAS No. ]:
6628-77-9

[ Name ]:
6-methoxypyridin-3-amin

[Synonym ]:
3-Pyridinamine, 6-methoxy-
6-Methoxy-pyridin-3-ylamine
6-Methoxy-3-pyridinamine
6-methoxypyridin-3-amine
6-methoxy-3-pyridinamin
2-methoxy-5-amino-pyridine
6-methoxypyridin-3-amin
6-Methoxy-3-pyridylamine
3-Amino-6-methoxypyridine
2-Methoxy-5-aminopyridine
MFCD00006264
EINECS 229-612-8
5-amino-2-methoxy-pyridin
5-Amino-2-methoxy
2-Methoxypyridin-5-amine

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
264.8±0.0 °C at 760 mmHg

[ Melting Point ]:
29-31 °C(lit.)

[ Molecular Formula ]:
C6H8N2O

[ Molecular Weight ]:
124.14

[ Flash Point ]:
109.5±21.8 °C

[ Exact Mass ]:
124.063660

[ PSA ]:
48.14000

[ LogP ]:
0.47

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.561

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Slightly soluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
US1836000
CHEMICAL NAME :
Pyridine, 5-amino-2-methoxy-
CAS REGISTRY NUMBER :
6628-77-9
BEILSTEIN REFERENCE NO. :
0115155
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H8-N2-O
MOLECULAR WEIGHT :
124.16
WISWESSER LINE NOTATION :
T6NJ BO1 EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 89,153,1947

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
US1836000

[ WGK Germany ]:
3

[ RTECS ]:
US1836000

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Methoxy-5-Bromopyridine
  • 2-Methoxy-5-nitropyridine
  • 2-Chloro-5-nitropyridine
  • 2-methoxy-5-nitropyridine N-oxide
  • JBSNF-000088
  • 2-Bromo-6-methoxypyridine
  • N-benzyl-6-methoxypyridin-3-amine
  • 2-Iodo-5-nitropyridine

DownStream

  • N-(6-Methoxy-3-pyridinyl)-1,2-dimethyl-N-{[5-(2-methylphenyl)-2-p yridinyl]methyl}-1H-imidazole-4-sulfonamide
  • 5-Fluorpyridin-2-ol
  • 2-Methoxyl-5-pyridineboronic acid pinacol ester
  • 5-Fluoro-2-methoxypyridine
  • Tert-butyl 6-methoxypyridin-3-ylcarbamate
  • 5-Hydrazino-2-methoxypyridine hydrochloride (1:1)
  • 6-Methoxy-1,5-naphthyridin-4-ol
  • 6-Methoxy-pyridine-3-sulfonyl chloride
  • 8-bromo-7-fluoro-2-methoxy-1,5-naphthyridine
  • 2-Bromo-5-fluoro-2-nitropyrdine

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 2-Bromo-6-methoxypyridin-3-amine
  • 5-Bromo-6-methoxypyridin-3-amine
  • 2-Ethyl-6-methoxypyridin-3-amine
  • N-ETHYL-6-METHOXYPYRIDIN-3-AMINE
  • 4-chloro-6-methoxypyridin-3-amine
  • 2-Fluoro-6-methoxypyridin-3-amine
  • (2S)-2-amino-1-(pyrimidin-5-yl)propan-1-one
  • (2S,3S)-2,3-Dihydroxybutanedioic acid-3-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}quinazoline-2,4(1H,3H)-dione (1:1)
  • 2-(Methylamino)-1-(4-methylfuran-2-yl)ethan-1-one
  • ethyl (2S)-azepane-2-carboxylate
  • tert-butyl (2R)-2,3-dihydro-1H-indole-2-carboxylate
  • (2R)-2-cyclohexyl-2-(trifluoroacetamido)acetic acid
  • 4-(4-Methylpiperazin-1-yl)pyrimidin-5-ol
  • 4,5-Dihydro-5-oxo-4-phenyl-3-(2-pyridinyl)-1H-1,2,4-triazole-1-propanenitrile
  • (2S)-1-(2,3-dimethylphenyl)propan-2-amine
  • (2S)-3-(adamantan-1-yl)-2-aminopropan-1-ol
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