FLUTOLANIL

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Names

[ CAS No. ]:
66332-96-5

[ Name ]:
FLUTOLANIL

[Synonym ]:
N-(3-propan-2-yloxyphenyl)-2-(trifluoromethyl)benzamide
α,α,α-trifluoro-3’-isopropoxy-o-toluanilide
3'-isopropoxy-2-trifloromethyl benzoic acid anilide
Prostar
o-trifluoromethyl-m'-isopropoxybenzoic anilide
3'-isopropoxy-2-trifluoromethyl benzoic acid anilide
N-(3-Isopropoxyphenyl)-2-(trifluoromethyl)benzamide
NNF-136
FLUTOLANIL
N-[3-(1-methylethoxy)phenyl]-2-(trifluoromethyl)benzamide
Folistar
N-[3-(propan-2-yloxy)phenyl]-2-(trifluoromethyl)benzamide
Flutolanil [BSI:ISO]
Moncut

Chemical & Physical Properties

[ Density]:
1.247g/cm3

[ Boiling Point ]:
339.1ºC at 760 mmHg

[ Melting Point ]:
108° (Araki, Yabutani); mp 104-105° (Araki, 1985)

[ Molecular Formula ]:
C17H16F3NO2

[ Molecular Weight ]:
323.31000

[ Flash Point ]:
158.9ºC

[ Exact Mass ]:
323.11300

[ PSA ]:
38.33000

[ LogP ]:
4.81790

[ Index of Refraction ]:
1.543

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV5581320
CHEMICAL NAME :
Benzamide, N-(3-(1-methylethoxy)phenyl)-2-(trifluoromethyl)-
CAS REGISTRY NUMBER :
66332-96-5
LAST UPDATED :
199701
DATA ITEMS CITED :
11
MOLECULAR FORMULA :
C17-H16-F3-N-O2
MOLECULAR WEIGHT :
323.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C209,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPIFAN Japan Pesticide Information. (Japan Plant Protection Assoc., 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) No.1-61, 1969-92. For publisher information, see AGJAEP. Volume(issue)/page/year: (47),23,1985
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,426,1991
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>10 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
18 gm/kg/30D-C
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
438 gm/kg/2Y-C
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
913 gm/kg/2Y-I
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from duodenum Gastrointestinal - nausea or vomiting Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 13,153,1988

Safety Information

[ Hazard Codes ]:
F+

[ RTECS ]:
CV5581320

[ Hazard Class ]:
3,6.1

[ HS Code ]:
2924299033

Synthetic Route

Precursor & DownStream

Precursor

  • 3-Isopropoxyaniline
  • 2-(Trifluoromethyl)benzoyl chloride

DownStream

  • 2-(Trifluoromethyl)benzamide
  • N-ethoxycarbonyl-2-(trifluoromethyl)benzamide
  • 2-(Trifluoromethyl)benzoic acid
  • N-(3-hydroxyphenyl)-2-(trifluoromethyl)benzamide
  • 2'-amino-4'-isopropoxyphenyl 2-trifluoromethyl ketone

Customs

[ HS Code ]: 2924299033

[ Summary ]:
2924299033 2,6-difluoro-n-((4-(trifluoromethyl)phenyl)carbamoyl)benzamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%


Related Compounds

  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • Ethyl (z)-2-amino-4-oxohex-2-enoate
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide