6-Amino-1,3-dimethyluracil

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Names

[ CAS No. ]:
6642-31-5

[ Name ]:
6-Amino-1,3-dimethyluracil

[Synonym ]:
MFCD00006552
6-Amino-1,3-dimethyluracil��6-Amino-1,3-dimethyl-2,4(1h,3h)-dione
2,4(1H,3H)-Pyrimidinedione, 6-amino-1,3-dimethyl-
6-Amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
6-amino-1,3-dimethylpyrimidine-2,4-dione
EINECS 229-662-0
6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
243.1±43.0 °C at 760 mmHg

[ Melting Point ]:
295 °C (dec.)(lit.)

[ Molecular Formula ]:
C6H9N3O2

[ Molecular Weight ]:
155.155

[ Flash Point ]:
100.8±28.2 °C

[ Exact Mass ]:
155.069473

[ PSA ]:
70.02000

[ LogP ]:
-0.27

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.551

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YQ8755000
CHEMICAL NAME :
Uracil, 6-amino-1,3-dimethyl-
CAS REGISTRY NUMBER :
6642-31-5
BEILSTEIN REFERENCE NO. :
0144390
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C6-H9-N3-O2
MOLECULAR WEIGHT :
155.18
WISWESSER LINE NOTATION :
T6NVNVJ A1 C1 EZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRMCE8 Farmaco. (Societa Chimica Italiana, Corso Strada Nova, 86, Casella Postale 227, 27100 Pavia, Italy) V.44- 1989- Volume(issue)/page/year: 45,223,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
56 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04375

Safety Information

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S22-S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
YQ8755000

[ HS Code ]:
2942000000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1,3-Dimethylurea
  • Cyanoacetic acid
  • 6-azido-1,3-dimethylpyrimidine-2,4-dione
  • 4-Amino-1,3-dimethyl-2,6-dioxopyrimidine-5-carbaldehyde
  • edaravone
  • Pyrimido[4,5-e]-1,2,4-triazine-6,8(5H,7H)-dione,5,7-dimethyl-
  • Ethyl cyanoacetate
  • Acetamide,2-cyano-N-methyl-N-[(methylamino)carbonyl]-
  • 1,3-dimethyl-6-[(triphenyl-λ5-phosphanylidene)amino]pyrimidine-2,4-dione
  • Ethanoic anhydride

DownStream

  • Uracil,5-acetamido-1,3-dimethyl-6-methylamino- (6CI)
  • 6-amino-5-[(4-amino-1,3-dimethyl-2,6-dioxopyrimidin-5-yl)methyl]-1,3-dimethylpyrimidine-2,4-dione
  • 6-[N-(2-Hydroxyethyl)amino]-1,3-dimethyl-2,4(1H,3H)-dione
  • 5,6-Diamino-1,3-Dimethyluracil
  • 5-NITRO-N-METHYL-2-(METHYLAMINO)PYRIDINE-3-CARBOXAMIDE
  • 2,4(1H,3H)-Pyrimidinedione,6-ethoxy-1,3-dimethyl-
  • 1,3-Dimethyluric acid
  • 6-Amino-1,2,3,4-tetrahydro-1,3-dimethyl-2,4-dioxo-5-pyrimidinecarbothioaldehyde
  • 1,3-Dimethyluracil
  • 2,4,5,6(1H,3H)-Pyrimidinetetrone,1,3-dimethyl-, 5-(2-phenylhydrazone)

Customs

[ HS Code ]: 2933599090

[ Summary ]:
2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Facile construction of substituted pyrimido[4,5-d]pyrimidones by transformation of enaminouracil.

J. Adv. Res. 4 , 115-21, (2015)

The reaction of 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (1) as a binucleophile with primary aromatic or heterocyclic amines and formaldehyde or aromatic (heterocyclic) aldehydes in a molar rat...


More Articles

Related Compounds

  • 5-Acetyl-6-amino-1,3-dimethyluracil
  • 5-Benzoyl-6-amino-1,3-dimethyluracil
  • Bis(6-amino-1,3-dimethyluracil-5-yl)methan
  • methyl 6-amino-1,3-dimethyluracil-5-dithiocarboxylate
  • 6-amino-1,3-dimethyluracil-5-carboxyaldehyde phenylhydrazone
  • 6-amino-1,3-dimethyl-5-(3-phenylprop-2-enoyl)pyrimidine-2,4-dione
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • 1-{1-[(5-bromofuran-2-yl)methyl]azetidin-3-yl}-2-cyclopropyl-1H-1,3-benzodiazole
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide