α1-Acid Glycoprotein, from human plasma

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Names

[ CAS No. ]:
66455-27-4

[ Name ]:
α1-Acid Glycoprotein, from human plasma

[Synonym ]:
MFCD00131224

Chemical & Physical Properties

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 10 mg/mL, clear, colorless

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
B

[ Safety Phrases ]:
S22;S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Protein-bound polysaccharide decreases invasiveness and proliferation in pancreatic cancer by inhibition of hedgehog signaling and HIF-1α pathways under hypoxia.

Cancer Lett. 335(2) , 289-98, (2013)

To develop an effective therapeutic approach to pancreatic ductal adenocarcinoma (PDAC), we focused on the antitumor mechanism of protein-bound polysaccharide (PSK) under hypoxia. PSK decreased prolif...

Biological mechanism and clinical effect of protein-bound polysaccharide K (KRESTIN(®)): review of development and future perspectives.

Surg. Today 42(1) , 8-28, (2012)

The mechanism of action of protein-bound polysaccharide K (PSK; KRESTIN(®)) involves the following actions: (1) recovery from immunosuppression induced by humoral factors such as transforming growth f...

Direct inhibition of the transforming growth factor-β pathway by protein-bound polysaccharide through inactivation of Smad2 signaling.

Cancer Sci. 103(2) , 317-24, (2012)

Transforming growth factor-β (TGF-β) is involved in the regulation of cell proliferation, differentiation, and apoptosis and is associated with epithelial-mesenchymal transition (EMT). Inhibition of t...

N-methyl-N-{1-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperidin-4-yl}pyridin-2-amine
2-{4-[Methyl(pyridin-2-yl)amino]piperidin-1-yl}quinoline-3-carbonitrile
3-Ethyl-3-(1-ethynylcyclopropyl)oxetane
N,N-dimethyl-2-{4-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl}pyrimidin-4-amine
4-[6-Methyl-2-(4-{pyrido[2,3-d]pyrimidin-4-yl}piperazin-1-yl)pyrimidin-4-yl]morpholine
N,N-dimethyl-4-{4-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl}pyrimidin-2-amine
4-[4-Methyl-6-(4-{pyrido[2,3-d]pyrimidin-4-yl}piperazin-1-yl)pyrimidin-2-yl]morpholine
4-[2-Methyl-6-(4-{pyrido[2,3-d]pyrimidin-4-yl}piperazin-1-yl)pyrimidin-4-yl]morpholine
N,N-dimethyl-6-{4-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl}pyrimidin-4-amine
N-[1-(6-chloro-1,3-benzoxazol-2-yl)piperidin-3-yl]-N-methylcyclopropanesulfonamide

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