4-pyridin-3-ylpyrimidin-2-amine

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Names

[ CAS No. ]:
66521-66-2

[ Name ]:
4-pyridin-3-ylpyrimidin-2-amine

[Synonym ]:
MFCD01317832
4-pyridin-3-ylpyrimidin-2-amine
2-Pyrimidinamine, 4-(3-pyridinyl)-
4-(3-Pyridinyl)-2-pyrimidinamine
4-(3-Pyridinyl)-2-pyrimidine amine
4-(pyridin-3-yl)pyrimidin-2-amine

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
439.9±37.0 °C at 760 mmHg

[ Melting Point ]:
191 °C

[ Molecular Formula ]:
C9H8N4

[ Molecular Weight ]:
172.187

[ Flash Point ]:
250.0±13.7 °C

[ Exact Mass ]:
172.074890

[ PSA ]:
64.69000

[ LogP ]:
0.37

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.642

[ Storage condition ]:
2~8℃

Safety Information

[ Hazard Codes ]:
T

[ Risk Phrases ]:
25-20/21/22

[ Safety Phrases ]:
45-36/37

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Carbonic acid-guanidine (1:2)
  • 1-(3-Pyridyl)-3-(dimethylamino)-2-propen-1-one
  • 2-Amino-4-chloropyrimidine
  • 3-Pyridylboronic acid
  • Guanidine hydrochloride
  • Guanidine nitrate
  • N-[4-(pyridin-3-yl)pyrimidin-2-yl]cyanamide
  • Cyanamide
  • 2-Nitroaniline
  • 3-Acetylpyridine

DownStream

  • 4-Chloromethyl-n-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide
  • methyl 4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoate
  • Nilotinib (AMN-107)
  • Imatinib (STI571)

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • N-(2-chlorophenyl)-4-pyridin-3-ylpyrimidin-2-amine
  • N-(4-methoxyphenyl)-4-pyridin-3-ylpyrimidin-2-amine
  • N-(2-methyl-5-nitrophenyl)-4-pyridin-3-ylpyrimidin-2-amine
  • N-(2-methyl-4-nitrophenyl)-4-pyridin-3-ylpyrimidin-2-amine
  • (4-pyridin-3-ylpyrimidin-2-yl)methanamine,hydrochloride
  • 4-methyl-6-pyridin-3-ylpyrimidin-2-amine