6-Chloronicotinoyl chloride

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Names

[ Name ]:
6-Chloronicotinoyl chloride

[Synonym ]:
3-Pyridinecarbonylchloride,6-chloro-,hydrochloride (1:1)
3-Pyridinecarbonyl chloride, 6-chloro-
6-Chloronicotinoyl chloride
6-Chlorpyridin-3-carbonylchlorid
MFCD00051775
6-Chloro-3-pyridylcarbonyl chloride hydrochloride
6-Chloro-nicotinoyl chloride
3-Pyridinecarbonylchloride,6-chloro-,hydrochloride (9CI)
Chlorure de 6-chloropyridine-3-carbonyle
6-Chloronicotinoyl chloride hydrochloride
2-Chloropyridine-5-carbonyl chloridehydrochloride

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
246.2±20.0 °C at 760 mmHg

[ Melting Point ]:
48-51ºC(lit.)

[ Molecular Formula ]:
C₆H₃Cl₂NO

[ Molecular Weight ]:
176.000

[ Flash Point ]:
102.7±21.8 °C

[ Exact Mass ]:
174.959167

[ PSA ]:
29.96000

[ LogP ]:
1.98

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.566

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
Xi,C

[ Risk Phrases ]:
36/37/38-34

[ Safety Phrases ]:
26-36-45-36/37/39

[ RIDADR ]:
UN 3261 8/PG 2

[ WGK Germany ]:
3

Articles

Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors.

J. Med. Chem. 37(17) , 2704-12, (1994)

This report describes the synthesis of 29 xanthines containing a chemoreactive chloroaryl, beta-chloroethylamino, alpha,beta-unsaturated carbonyl, bromoacetyl, 3-(fluorosulfonyl)benzoyl, or 4-(fluoros...

Asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine: preparation, resolution and biological activities toward insects and their nerve preparations.

Biosci. Biotechnol. Biochem. 67(5) , 980-8, (2003)

The asymmetric chloronicotinyl insecticide, 1-[1-(6-chloro-3-pyridyl)ethyl]-2-nitroiminoimidazolidine, was prepared, and the absolute configurations of the enantiomers were determined by an X-ray anal...

[³H] imidacloprid: Synthesis of a candidate radioligand for the nicotinic acetylcholine receptor. Latli B and Casida JE.

J. Labelled Comp. Radiopharm. 31(8) , 609-613, (1992)

6-Chloronicotinoyl chloride
5-bromo-6-chloronicotinoyl chloride
6-chloride-thiochroMan-4-ylamine,hydrochloride
Pyrimidine, 4-cyclopropyl-2,6-dimethyl- (9CI)
3-Pyridinecarbonyl chloride, 4-chloro-2,6-dimethyl- (9CI)
2-Chloro-6-methylnicotinoylchloride
N-[(3-Pyridin-4-ylphenyl)methyl]but-2-ynamide
2-Chloro-N-[4-(2,6-difluorophenyl)butan-2-yl]acetamide
N-(3-Pyrazol-1-ylpentyl)but-2-ynamide
N-[2-(2-Methylpyrrolidin-1-yl)-2-oxoethyl]but-2-ynamide
N-(1-Phenyl-3-piperidin-1-ylpropyl)but-2-ynamide
N-(6-Oxo-1-phenylpiperidin-3-yl)but-2-ynamide
4-(Oxiran-2-ylmethoxy)naphthalene-1-carbonitrile
4-[3-(Oxiran-2-ylmethoxy)phenyl]oxane
tert-butyl 2-(3-acetyl-7-(hydroxymethyl)-5-(2-methylpyrimidin-5-yl)-1H-indazol-1-yl)acetate
N-[2-(pyrrolidin-1-yl)-2-(1,3-thiazol-2-yl)ethyl]but-2-ynamide

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