(R)-(-)-5-(Hydroxymethyl)-2-pyrrolidinone

Suppliers

Names

[ Name ]:
(R)-(-)-5-(Hydroxymethyl)-2-pyrrolidinone

[Synonym ]:
T5MVTJ E1Q &&(R)-(-)- Form
(5S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5R)-
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5S)-(+)-
(R)-(-)-5-hydroxymethyl-2-pyrrolidinone
(5S)-5-(Hydroxymethyl)pyrrolidin-2-on
(5R)-5-(Hydroxymethyl)pyrrolidin-2-one
(5R)-(-)-5-(Hydroxymethyl)pyrrolidin-2-one
(5S)-(+)-5-(Hydroxymethyl)pyrrolidin-2-one
(5R)-5-(Hydroxymethyl)-2-pyrrolidinone
T5MVTJ E1Q &&(S)-(+)- Form
MFCD00077791
(5R)-(-)-5-(Hydroxymethyl)-2-pyrrolidinone
2-Pyrrolidinone, 5-(hydroxymethyl)-, (5R)-(-)-
(5S)-5-(Hydroxymethyl)-2-pyrrolidinone
(5S)-5-(hydroxymethyl)pyrrolidin-2-one

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
346.0±15.0 °C at 760 mmHg

[ Melting Point ]:
83-85ºC(lit.)

[ Molecular Formula ]:
C₅H₉NO₂

[ Molecular Weight ]:
115.131

[ Flash Point ]:
163.0±20.4 °C

[ Exact Mass ]:
115.063332

[ PSA ]:
49.33000

[ LogP ]:
-2.49

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.476

[ Storage condition ]:
-20°C Freezer, Under Inert Atmosphere

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933790090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(R)-Methyl 5-oxopyrrolidine-2-carboxylate
H-D-Pyr-OEt
D(-)-Glutamic acid
D-Pyroglutamic acid
D-glutamic acid diethyl ester

DownStream

D-Pyroglutamic acid
(5R)-5-(Brommethyl)pyrrolidin-2-on
(5R)-5-[[[(tert-Butyl)dimethylsilyl]oxy]methyl]-2-pyrrolidinone
2-Methyl-2-propanyl (2R)-2-(hydroxymethyl)-5-oxo-1-pyrrolidinecarboxylate
(R)-5-(CHLOROMETHYL)PYRROLIDIN-2-ONE
(S)-5-Methylpyrrolidin-2-One
(3S,7aR)-3-Phenyltetrahydro-5H-pyrrolo[1,2-c][1,3]oxazol-5-one
(3S,7aR)-3-Phenyl-1,7a-dihydro-5H-pyrrolo[1,2-c][1,3]oxazol-5-one

Customs

[ HS Code ]: 2933790090

[ Summary ]:
2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Articles

J. Am. Chem. Soc. 114 , 1495, (1992)

(R)-1-BENZYL-5-HYDROXYMETHYL-2-PYRROLIDINONE
(R)-1-AMINO-2,2-DIMETHYLCYCLOPROPANECARBOXYLICACID
(S)-(+)-5-(Hydroxymethyl)-2-pyrrolidinone p-toluenesulfonate
(S)-1-BENZYL-5-HYDROXYMETHYL-2-PYRROLIDINONE
3,3-dimethyl-5-hydroxymethyl-2-pyrrolidinone
(3R,5S)-3-allyl-5-hydroxymethyl-2-pyrrolidinone
Methyl (R)-4-methylpiperazine-2-carboxylate
(2S)-1-[[4-[1,2-Dimethyl-5-(1H-pyrrolo[2,3-b]pyridin-5-yl)-1H-imidazol-4-yl]-2-pyrimidinyl]amino]-2-propanol
N-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)-2-(1H-pyrazol-1-yl)acetamide
Spiro[cyclopentane-1,3a(2)(4a(2)H)-pyrrolo[1,2-a]pyrazine], hexahydro-, (8a(2)aS)-
N-(2-(4-fluorophenoxy)ethyl)-2-(1H-pyrazol-1-yl)acetamide
(3R)-3-[(6-chloro-2-pyrazinyl)amino]-1-pyrrolidinecarboxylic acid 1,1-dimethylethyl ester
(R)-3-(4-chloro-5-iodo-pyrrolo[2,3-d]pyrimidin-7-yl)-pyrrolidine-1-carboxylic acid tert-butyl ester
(S)-tert-butyl 3-(4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyrrolidine-1-carboxylate
1-(4-(methylsulfonyl)piperazin-1-yl)-2-(1H-pyrazol-1-yl)ethanone
2-(1H-pyrazol-1-yl)-N-(2,2,2-trifluoroethyl)acetamide

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.