BIO

Suppliers

Names

[ Name ]:
BIO

[Synonym ]:
6-Bromoindirubin-3'-oxime
6-bromoindirubin-3'-monoxime
(3Z)-6-Bromo-3-[(3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-1,3-dihydro-2H-indol-2-one
2H-Indol-2-one, 6-bromo-3-[(3E)-1,3-dihydro-3-(hydroxyimino)-2H-indol-2-ylidene]-1,3-dihydro-, (3Z)-
(2'Z,3'E)-6-Bromoindirubin-3'-oxime

Chemical & Physical Properties

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
554.3±50.0 °C at 760 mmHg

[ Melting Point ]:
300°C(lit.)

[ Molecular Formula ]:
C₁₆H₁₀BrN₃O₂

[ Molecular Weight ]:
356.173

[ Flash Point ]:
289.0±30.1 °C

[ Exact Mass ]:
354.995636

[ PSA ]:
73.72000

[ LogP ]:
2.41

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.802

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Characterization of Leber Congenital Amaurosis-associated NMNAT1 Mutants.

J. Biol. Chem. 290 , 17228-38, (2015)

Leber congenital amaurosis 9 (LCA9) is an autosomal recessive retinal degeneration condition caused by mutations in the NAD(+) biosynthetic enzyme NMNAT1. This condition leads to early blindness but n...

Inhibitors of Matriptase-2 Based on the Trypsin Inhibitor SFTI-1.

ChemBioChem. 16 , 1601-7, (2015)

A series of 17 new analogues of trypsin inhibitor SFTI-1 were designed and synthesized to obtain matriptase-2 inhibitors. A number of the modified bicyclic peptides displayed much higher affinity towa...

Novel recA-Independent Horizontal Gene Transfer in Escherichia coli K-12.

PLoS ONE 10 , e0130813, (2015)

In bacteria, mechanisms that incorporate DNA into a genome without strand-transfer proteins such as RecA play a major role in generating novelty by horizontal gene transfer. We describe a new illegiti...

BIO