trans-2-Chloro-3-(chloromethyl)oxirane

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Names

[ CAS No. ]:
66826-73-1

[ Name ]:
trans-2-Chloro-3-(chloromethyl)oxirane

[Synonym ]:
cis-1,3-Dichlorpropenoxid
trans-1,3-Dichloropropene oxide
trans-1,3-Dichloro-1,2-epoxypropane
trans-Dcpo

Chemical & Physical Properties

[ Density]:
1.41g/cm3

[ Boiling Point ]:
173.4ºC at 760 mmHg

[ Molecular Formula ]:
C3H4Cl2O

[ Molecular Weight ]:
126.96900

[ Flash Point ]:
151.8ºC

[ Exact Mass ]:
125.96400

[ PSA ]:
12.53000

[ LogP ]:
1.18890

[ Index of Refraction ]:
1.474

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX9683000
CHEMICAL NAME :
Propane, 1,3-dichloro-1,2-epoxy-, (E)-
CAS REGISTRY NUMBER :
66826-73-1
BEILSTEIN REFERENCE NO. :
4652844
LAST UPDATED :
199612
DATA ITEMS CITED :
6
MOLECULAR FORMULA :
C3-H4-Cl2-O
MOLECULAR WEIGHT :
126.97
WISWESSER LINE NOTATION :
T3OTJ BG C1G -T

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
400 mg/kg/73W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
20 mg/kg/71W-I
TOXIC EFFECTS :
Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TYPE OF TEST :
Morphological transformation
TEST SYSTEM :
Rodent - hamster Embryo
DOSE/DURATION :
10 umol/L
REFERENCE :
JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 69,531,1982

Safety Information

[ WGK Germany ]:
3

[ RTECS ]:
UC8310000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2910900090

Precursor & DownStream

Precursor

DownStream

  • 2,3-dichloropropionaldehyde
  • 2,5-Dihydroxy-3,6-bis(chloromethyl)-1,4-dioxane
  • 2-Hydroxy-3-chloropropanal

Customs

[ HS Code ]: 2910900090

[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Compounds

  • 2-chloro-3-(chloromethyl)oxirane
  • trans-2-Chloro-3-[4-(4-chlorophenyl)cyclohexyl]-1,4-naphthalenedione
  • TRANS-2-CHLORO-3-BENZYLOXY-4-METHOXY-BE&
  • TRANS-2-CHLORO-3-HYDROXY-4-METHOXY-BETA&
  • (Z)-2-chloro-3-(chloromethyl)-4-oxobut-2-enoic acid
  • N-(2-CHLORO-3-(CHLOROMETHYL)PHENYL)-N-(METHYLSULFONYL)METHANESULFONAMIDE