Synephrine tartrate

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Names

[ CAS No. ]:
67-04-9

[ Name ]:
Synephrine tartrate

[Synonym ]:
EINECS 240-647-8
Sympathomim

Chemical & Physical Properties

[ Boiling Point ]:
341.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₁₉NO₈

[ Molecular Weight ]:
317.29200

[ Flash Point ]:
163.4ºC

[ Exact Mass ]:
317.11100

[ PSA ]:
167.55000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DO7875000

CAS REGISTRY NUMBER :: 67-04-9

LAST UPDATED :: 199601

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C9-H13-N-O2.C4-H6-O6

MOLECULAR WEIGHT :: 317.33

WISWESSER LINE NOTATION :: QR DYQ1M1 & 2 &QVYQYQVQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4450 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2730 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraduodenal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3050 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 180,155,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 237,171,1959

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

REFERENCE :: AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 166,437,1932 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 2087 mg/kg

SEX/DURATION :: female 7-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - other developmental abnormalities

REFERENCE :: AAMLAR Atti della Accademia Medica Lombarda. (c/o Prof. W. Montorsi, Festa del Perdono 3, Milan, Italy) V.20-29, 1931-40; New series: V.15- 1960- Volume(issue)/page/year: 25,203,1970

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intramuscular

DOSE :: 1044 mg/kg

SEX/DURATION :: female 7-16 day(s) after conception

TOXIC EFFECTS :: Reproductive - Specific Developmental Abnormalities - musculoskeletal system

REFERENCE :: AAMLAR Atti della Accademia Medica Lombarda. (c/o Prof. W. Montorsi, Festa del Perdono 3, Milan, Italy) V.20-29, 1931-40; New series: V.15- 1960- Volume(issue)/page/year: 25,203,1970

Precursor & DownStream

Precursor

DownStream

Related Compounds

Synephrine tartrate
synephrine tartrate
synephrine
Synephrine hydrochloride
Hydroxybutorphanol tartrate
Xanomeline tartrate
ethylN-[(2E)-3-oxo-2-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}butanoyl]carbamate
1,1-Diethyl-2-hydroxy-3-oxotriazane
1H-Indazole, 6-chloro-3-(1H-indol-2-yl)-
N'-(3,4-dihydroxybenzylidene)-2-hydroxybenzohydrazide
5,6-Dimethyl-2-phenyl-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
2-[4-Methyl-2-(methylsulfanyl)-6-oxo-1,6-dihydro-5-pyrimidinyl]ethyl acetate
6-methyl-3-[(Z)-(2-phenylhydrazino)methylidene]-2H-pyran-2,4-dione
2-Amino-9-((2R,4S,5R)-4-hydroxy-5-methyltetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
2-Methylsulfanyl-6-phenyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one
2-(6-Formamidopyridin-2-yl)-2-hydroxyiminoacetic acid

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