Tetrac

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Names

[ CAS No. ]:
67-30-1

[ Name ]:
Tetrac

[Synonym ]:
5-diiodophenoxy)-3
Thyroacetic acid,3,3',5,5'-tetraiodo
3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid
Tetrac
MFCD00055932
[4-(4-hydroxy-3
4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylacetic acid
Benzeneacetic acid,3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)
3,3',5,5'-TETRAIODOTHYROACETIC ACID
Tetraiodothyroacetic acid
Acide 3,5,3',5'-tetraiodothyroacetique [French]
5-diiodophenyl] acetic acid
EINECS 200-649-1

Chemical & Physical Properties

[ Density]:
2.727g/cm3

[ Boiling Point ]:
544.8ºC at 760 mmHg

[ Melting Point ]:
230 °C

[ Molecular Formula ]:
C14H8I4O4

[ Molecular Weight ]:
747.82900

[ Flash Point ]:
283.3ºC

[ Exact Mass ]:
747.66000

[ PSA ]:
66.76000

[ LogP ]:
5.23000

[ Index of Refraction ]:
1.801

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
T+

[ Risk Phrases ]:
28

[ Safety Phrases ]:
45

[ RIDADR ]:
UN 2811 6.1/PG 1

[ RTECS ]:
CY1585800

[ Hazard Class ]:
6.1

[ HS Code ]:
2918990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 3,5-Diiodothyroacetic Acid
  • (4-hydroxy-3,5-dinitro-phenyl)-acetic acid ethyl ester
  • [4-(4-methoxy-phenoxy)-3,5-dinitro-phenyl]-acetic acid ethyl ester
  • Mequinol
  • ethyl 3,5-diiodo-4-(4-methoxyphenoxy)phenylacetate
  • ethyl 2-(3,5-diamino-4-(4-methoxyphenoxy)phenyl)acetate
  • 1-(4-chloromethyl-2,6-diiodo-phenoxy)-4-methoxy-benzene
  • [3,5-diiodo-4-(4-methoxy-phenoxy)-phenyl]-acetonitrile

DownStream

Customs

[ HS Code ]: 2918990090

[ Summary ]:
2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

Tetraiodothyroacetic acid-tagged liposomes for enhanced delivery of anticancer drug to tumor tissue via integrin receptor

J. Control. Release 164(2) , 213-20, (2012)

Nanoparticles have demonstrated potential for promoting drug delivery to tumor sites and enhancing uptake. Here, we report tetraiodothyroacetic acid (tetrac) as a promising new targeting moiety for de...

Tetraiodothyroacetic acid and tetraiodothyroacetic acid nanoparticle effectively inhibit the growth of human follicular thyroid cell carcinoma.

Thyroid 20(3) , 281-6, (2010)

Tetraiodothyroacetic acid (tetrac) is a deaminated analogue of L-thyroxine that blocks the actions of L-thyroxine and 3,5,3'-triiodo-L-thyronine at the cell surface receptor for thyroid hormone on int...

Tetraiodothyroacetic acid and its nanoformulation inhibit thyroid hormone stimulation of non-small cell lung cancer cells in vitro and its growth in xenografts.

Lung Cancer 76(1) , 39-45, (2012)

Thyroid hormone stimulates cell proliferation of several types of cancers and stimulates cancer-relevant angiogenesis. In the present study, we investigated the proliferative effect of thyroid hormone...


More Articles

Related Compounds

  • 3-({3-[4-(Ethoxycarbonyl)benzyl]-2,4-dioxo-1,3-thiazolidin-5-yl}amino)benzoic acid
  • (1-(Methylsulfonyl)piperidin-3-yl)(4-phenylpiperazin-1-yl)methanone
  • 1-[(5-chloro-2-methoxyphenyl)sulfonyl]-N-(4-sulfamoylphenyl)piperidine-3-carboxamide
  • Methyl 3-{[(3-bromophenyl)carbonyl]amino}-4-(4-ethylpiperazin-1-yl)benzoate
  • Methyl 3-{[2-(4-chlorophenoxy)-2-methylpropanoyl]amino}-4-(4-ethylpiperazin-1-yl)benzoate
  • 1-[5-(4-methoxyphenyl)-7-(4-methylphenyl)-6,7-dihydro[1,2,4]triazolo[1,5-a]pyrimidin-4(5H)-yl]pentan-1-one
  • 2-Methyl-3-furancarbothioamide
  • 7-Benzyl-3-(tert-butyl)-5-methyl-6-phenylbenzofuran
  • 1-Benzyl-2-methylhydrazine dihydrochloride
  • 5-Acetyl-2-methyl-1-(tetrahydro-2H-pyran-4-yl)-1H-imidazole
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