5-hydroxymethylfurfural

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Names

[ CAS No. ]:
67-47-0

[ Name ]:
5-hydroxymethylfurfural

[Synonym ]:
HMF
EINECS 200-654-9
5-(Hydroxymethyl)furan-2-carboxaldehyde
T5OJ BVH E1Q
5-(Hydroxymethyl)-2-furancarboxaldehyde
5-(Hydroxymethyl)furan-2-carbaldehyde
Aes-103
5-(Hydroxymethyl)furfural
5-Hydroxymethylfurfural
2-Furancarboxaldehyde, 5-(hydroxymethyl)-
MFCD00003234
2-furaldehyde, 5-(hydroxymethyl)-

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
291.5±30.0 °C at 760 mmHg

[ Melting Point ]:
28-34 °C(lit.)

[ Molecular Formula ]:
C6H6O3

[ Molecular Weight ]:
126.110

[ Flash Point ]:
79.4±0.0 °C

[ Exact Mass ]:
126.031693

[ PSA ]:
50.44000

[ LogP ]:
-0.45

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.563

[ Storage condition ]:
2-8°C

[ Stability ]:
Light Sensitive, Very Hygroscopic

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
LT7031100
CHEMICAL NAME :
2-Furaldehyde, 5-(hydroxymethyl)-
CAS REGISTRY NUMBER :
67-47-0
BEILSTEIN REFERENCE NO. :
0110889
LAST UPDATED :
199712
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C6-H6-O3
MOLECULAR WEIGHT :
126.12
WISWESSER LINE NOTATION :
T5OJ BVH E1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Lung
DOSE/DURATION :
2 gm/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 227,117,1989

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
LT7031100

[ Packaging Group ]:
III

[ HS Code ]:
2932190090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • L-(−)-Sorbose
  • D-fructofuranose
  • D-(+)-Glucose
  • Ethanol
  • Methanol
  • Fructose
  • sucrose
  • D-glucopyranose
  • D-Fructopyranose
  • D-fructofuranose

DownStream

  • 2-(dimethoxymethyl)-5-(methoxymethyl)furan
  • hexane-1,2,5-triol
  • 2,5-Anhydro-3,4-dideoxyhexitol
  • UNII:W45XXM0XWE
  • 1-hydroxyhexane-2,5-dione
  • Formic Acid
  • 2-Ketoglutaric acid
  • Succinic acid
  • Dimethyl furan-2,5-dicarboxylate

Customs

[ HS Code ]: 2932190090

[ Summary ]:
2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

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