HSDB 3314
Suppliers
Names
[ CAS No. ]:
67-96-9
[ Name ]:
HSDB 3314
[Synonym ]:
Dihydrotachysterin2
AT-10
ANTITANIL
Dygrayl
parterol
MFCD00867069
dygratyl
Tachyrol
DIHYDROTACHYSTEROL
dihydral
dht2
EINECS 200-672-7
Chemical & Physical Properties
[ Density]:
1.003 g/cm3
[ Boiling Point ]:
499.5ºC at 760 mmHg
[ Melting Point ]:
131ºC
[ Molecular Formula ]:
C28H46O
[ Molecular Weight ]:
398.66400
[ Flash Point ]:
217.6ºC
[ Exact Mass ]:
398.35500
[ PSA ]:
20.23000
[ LogP ]:
7.72090
[ Index of Refraction ]:
1.569
[ Storage condition ]:
-20°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WW0600000
- CHEMICAL NAME :
- Tachysterol, dihydro-
- CAS REGISTRY NUMBER :
- 67-96-9
- LAST UPDATED :
- 199504
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C28-H46-O
- MOLECULAR WEIGHT :
- 398.74
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 288 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,330,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 104 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,330,1982 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 150 mg/kg
- SEX/DURATION :
- female 1-5 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- CUSCAM Current Science. (Current Science Assoc., Sadashivanagar P.O., Bangalore 560 080, India) V.1- 1932- Volume(issue)/page/year: 41,181,1972 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X5329 No. of Facilities: 19 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 403 (estimated) No. of Female Employees: 189 (estimated)
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
Missing Phrase - N15.00950417
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
22
[ Safety Phrases ]:
36
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
WW0600000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)
Synthetic Route
Articles
Perit. Dial. Int. 25(4) , 362-6, (2005)
Peritoneal dialysis (PD) patients are at risk for 25(OH) vitamin D deficiency due to effluent loss in addition to traditional risk factors.To measure 25(OH) vitamin D deficiency in prevalent PD patien...
Brain Res. Mol. Brain Res. 133(2) , 215-23, (2005)
3-nitropropionic acid (3-NPA), a complex II inhibitor of the electron transport chain, causes Huntington disease-like symptoms after administration into animals. However, primary mechanisms of cell de...
Biochem. Biophys. Res. Commun. 303(1) , 52-8, (2003)
Vitamin D-elicited hypercalcemia/hypercalciuria is associated with polyuria in humans and in animal models. In rats, dihydrotachysterol (DHT) induces AQP2 water channel downregulation despite unaltere...